SEPN

Septerna Inc

89 hedge funds and large institutions have $470M invested in Septerna Inc in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 31 increasing their positions, 19 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more funds holding

Funds holding:

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

2.2% less ownership

Funds ownership: 101.91%99.71% (-2.2%)

97% less call options, than puts

Call options by funds: $440K | Put options by funds: $12.6M

Holders
89
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$440K
Puts
$12.6M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
1
$73.9M
2
$65.7M
3
$49.5M
4
$46.5M
5
$44.5M
6
$33.3M
7
$23.3M
8
$15M
9
$14.9M
10
$14.7M
11
$13.1M
12
$8.96M
13
$6.2M
14
$6.18M
15
$5.85M
16
$5.72M
17
$5.71M
18
$5.16M
19
$3.91M
20
$3.11M
21
$2.99M
22
$2.35M
23
$1.76M
24
$1.64M
25
$1.63M