WP
SEPN

Woodline Partners’s Septerna Inc SEPN Stock Holding History

Woodline Partners’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$6.21M Buy
+185,535
New +$5.26M 0.02% 641
2026
Q1 		– Sell
-385,310
Closed -$10.7M – 1167
2025
Q4 		$10.7M Buy
385,310
+102,725
+36% +$2.45M 0.04% 441
2025
Q3 		$5.32M Hold
282,585
– – 0.03% 551
2025
Q2 		$2.99M Sell
282,585
-300,000
-51% -$2.47M 0.02% 656
2025
Q1 		$3.37M Buy
582,585
+282,585
+94% +$3.23M 0.02% 593
2024
Q4 		$6.87M Buy
+300,000
New +$7.09M 0.05% 423

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Woodline Partners's SEPN Position: Q2 2026 in Review

Woodline Partners opened a new position in Septerna Inc (SEPN) in Q2 2026: 185,535 shares worth $6.21M. The stake represents 0.02% of the portfolio and ranks #641 among its holdings. This is a return to the name: Woodline Partners previously reported a position in SEPN as recently as Q4 2025.

Woodline Partners first reported a position in SEPN in Q4 2024 and has held it in 6 quarters since. The position peaked at $10.7M in Q4 2025. 153 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Woodline Partners held 185,535 shares of Septerna Inc worth $6.21M as of Q2 2026.
  • Septerna Inc was a new Woodline Partners position in Q2 2026.
  • Septerna Inc made up 0.02% of Woodline Partners's portfolio in Q2 2026, its #641 holding.
  • Woodline Partners first reported a position in Septerna Inc in Q4 2024 and has held it in 6 quarters since.
  • Woodline Partners's Septerna Inc position peaked at $10.7M in Q4 2025.
  • 153 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Woodline Partners's 13F filing for Q2 2026, filed 14 Aug 2026.