Goldman Sachs
SEPN

Goldman Sachs’s Septerna Inc SEPN Stock Holding History

Goldman Sachs’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$103M Buy
3,062,766
+156,339
+5% +$4.44M 0.01% 1207
2026
Q1 		$69.8M Buy
2,906,427
+191,298
+7% +$5.03M 0.01% 1303
2025
Q4 		$75.7M Buy
2,715,129
+1,260,409
+87% +$30.1M 0.01% 1186
2025
Q3 		$27.4M Buy
1,454,720
+38,406
+3% +$504K ﹤0.01% 1951
2025
Q2 		$15M Sell
1,416,314
-33,085
-2% -$272K ﹤0.01% 2383
2025
Q1 		$8.39M Sell
1,449,399
-224,958
-13% -$2.57M ﹤0.01% 2864
2024
Q4 		$38.3M Buy
+1,674,357
New +$39.6M 0.01% 1526

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Goldman Sachs's SEPN Position: Q2 2026 in Review

Goldman Sachs increased its Septerna Inc (SEPN) stake by 5.4% in Q2 2026, buying an estimated $4.44M and bringing the position to 3,062,766 shares worth $103M. The position accounts for 0.01% of the portfolio, ranked #1207.

Goldman Sachs first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Goldman Sachs held 3,062,766 shares of Septerna Inc worth $103M as of Q2 2026.
  • Goldman Sachs bought 156,339 Septerna Inc shares in Q2 2026, an estimated $4.44M.
  • Septerna Inc made up 0.01% of Goldman Sachs's portfolio in Q2 2026, its #1207 holding.
  • Goldman Sachs first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Goldman Sachs's 13F filing for Q2 2026, filed 14 Aug 2026.