Vanguard Capital Management
SEPN

Vanguard Capital Management’s Septerna Inc SEPN Stock Holding History

Vanguard Capital Management’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$40.9M Buy
1,221,673
+24,711
+2% +$701K ﹤0.01% 2059
2026
Q1 		$28.8M Buy
+1,196,962
New +$31.5M ﹤0.01% 2155

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Vanguard Capital Management's SEPN Position: Q2 2026 in Review

Vanguard Capital Management increased its Septerna Inc (SEPN) stake by 2.1% in Q2 2026, buying an estimated $701K and bringing the position to 1,221,673 shares worth $40.9M. The position accounts for ﹤0.01% of the portfolio, ranked #2059.

Vanguard Capital Management first reported a position in SEPN in Q1 2026 and has held it in 2 quarters since. 152 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Vanguard Capital Management held 1,221,673 shares of Septerna Inc worth $40.9M as of Q2 2026.
  • Vanguard Capital Management bought 24,711 Septerna Inc shares in Q2 2026, an estimated $701K.
  • Septerna Inc made up ﹤0.01% of Vanguard Capital Management's portfolio in Q2 2026, its #2059 holding.
  • Vanguard Capital Management first reported a position in Septerna Inc in Q1 2026 and has held it in 2 quarters since.
  • 152 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Vanguard Capital Management's 13F filing for Q2 2026, filed 13 Aug 2026.