BlackRock
SEPN

BlackRock’s Septerna Inc SEPN Stock Holding History

BlackRock’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$64.7M Buy
1,932,088
+109,914
+6% +$3.12M ﹤0.01% 2509
2026
Q1 		$43.8M Buy
1,822,174
+20,846
+1% +$548K ﹤0.01% 2591
2025
Q4 		$50.2M Buy
1,801,328
+341,533
+23% +$8.16M ﹤0.01% 2514
2025
Q3 		$27.5M Buy
1,459,795
+68,995
+5% +$905K ﹤0.01% 2891
2025
Q2 		$14.7M Buy
1,390,800
+132,487
+11% +$1.09M ﹤0.01% 3201
2025
Q1 		$7.29M Sell
1,258,313
-418,822
-25% -$4.78M ﹤0.01% 3475
2024
Q4 		$38.4M Buy
+1,677,135
New +$39.7M ﹤0.01% 2623

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

BlackRock's SEPN Position: Q2 2026 in Review

BlackRock increased its Septerna Inc (SEPN) stake by 6% in Q2 2026, buying an estimated $3.12M and bringing the position to 1,932,088 shares worth $64.7M. The position accounts for ﹤0.01% of the portfolio, ranked #2509.

BlackRock first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • BlackRock held 1,932,088 shares of Septerna Inc worth $64.7M as of Q2 2026.
  • BlackRock bought 109,914 Septerna Inc shares in Q2 2026, an estimated $3.12M.
  • Septerna Inc made up ﹤0.01% of BlackRock's portfolio in Q2 2026, its #2509 holding.
  • BlackRock first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on BlackRock's 13F filing for Q2 2026, filed 7 Aug 2026.