SCM
SEPN

Soleus Capital Management’s Septerna Inc SEPN Stock Holding History

Soleus Capital Management’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$9.21M Hold
275,000
– – 0.32% 58
2026
Q1 		$6.61M Sell
275,000
-108,368
-28% -$2.85M 0.27% 58
2025
Q4 		$10.7M Buy
383,368
+365,108
+1,999% +$8.72M 0.39% 50
2025
Q3 		$343K Sell
18,260
-57,196
-76% -$751K 0.02% 85
2025
Q2 		$798K Sell
75,456
-675,897
-90% -$5.57M 0.05% 88
2025
Q1 		$4.35M Buy
751,353
+75,944
+11% +$867K 0.31% 52
2024
Q4 		$15.5M Buy
+675,409
New +$16M 0.97% 33

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Soleus Capital Management's SEPN Position: Q2 2026 in Review

Soleus Capital Management held its Septerna Inc (SEPN) position steady in Q2 2026 at 275,000 shares worth $9.21M. The position accounts for 0.32% of the portfolio, ranked #58.

Soleus Capital Management first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. The position peaked at $15.5M in Q4 2024. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Soleus Capital Management held 275,000 shares of Septerna Inc worth $9.21M as of Q2 2026.
  • Soleus Capital Management left its Septerna Inc share count unchanged in Q2 2026.
  • Septerna Inc made up 0.32% of Soleus Capital Management's portfolio in Q2 2026, its #58 holding.
  • Soleus Capital Management first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • Soleus Capital Management's Septerna Inc position peaked at $15.5M in Q4 2024.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Soleus Capital Management's 13F filing for Q2 2026, filed 11 Aug 2026.