CCM
SEPN

Catalio Capital Management’s Septerna Inc SEPN Stock Holding History

Catalio Capital Management’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$7.07M Hold
294,360
– – 1.48% 25
2025
Q4 		$8.21M Hold
294,360
– – 1.45% 28
2025
Q3 		$5.54M Hold
294,360
– – 1.02% 27
2025
Q2 		$3.11M Sell
294,360
-729,885
-71% -$6.01M 0.65% 26
2025
Q1 		$5.93M Hold
1,024,245
– – 1.44% 19
2024
Q4 		$23.5M Buy
+1,024,245
New +$24.2M 5.13% 9

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Catalio Capital Management's SEPN Position: Q1 2026 in Review

Catalio Capital Management held its Septerna Inc (SEPN) position steady in Q1 2026 at 294,360 shares worth $7.07M. The position accounts for 1.48% of the portfolio, ranked #25.

Catalio Capital Management first reported a position in SEPN in Q4 2024 and has held it in 6 quarters since. The position peaked at $23.5M in Q4 2024. 124 funds tracked by Wall St. Rank hold SEPN as of Q1 2026.

  • Catalio Capital Management held 294,360 shares of Septerna Inc worth $7.07M as of Q1 2026.
  • Catalio Capital Management left its Septerna Inc share count unchanged in Q1 2026.
  • Septerna Inc made up 1.48% of Catalio Capital Management's portfolio in Q1 2026, its #25 holding.
  • Catalio Capital Management first reported a position in Septerna Inc in Q4 2024 and has held it in 6 quarters since.
  • Catalio Capital Management's Septerna Inc position peaked at $23.5M in Q4 2024.
  • 124 funds tracked by Wall St. Rank held Septerna Inc as of Q1 2026.

Based on Catalio Capital Management's 13F filing for Q1 2026, filed 15 May 2026.