VR Adviser’s Septerna Inc SEPN Stock Holding History

VR Adviser’s Portfolio SEPN Stock Details SEPN Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	–	Sell	-506,056	Closed	-$12.2M	–	37
2026 Q1	$12.2M	Sell	506,056 -104,752	-17%	-$2.75M	0.45%	29
2025 Q4	$17M	Hold	610,808	–	–	0.84%	23
2025 Q3	$11.5M	Buy	610,808 +70,355	+13%	+$923K	0.65%	27
2025 Q2	$5.71M	Buy	+540,453	New	+$4.45M	0.43%	26

Other funds holding SEPN

RCM

RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return

TGV

TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

TGV

TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return

Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return

Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

Jupiter Topco New York $245B AUM

VR Adviser's SEPN Position: Q2 2026 in Review

VR Adviser sold out of Septerna Inc (SEPN) in Q2 2026, closing a stake of 506,056 shares — an estimated $12.2M sold.

VR Adviser first reported a position in SEPN in Q2 2025 and held it in 4 quarters. The position peaked at $17M in Q4 2025. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

VR Adviser reported no remaining Septerna Inc position as of Q2 2026 after selling out during the quarter.
VR Adviser sold 506,056 Septerna Inc shares in Q2 2026, an estimated $12.2M.
VR Adviser first reported a position in Septerna Inc in Q2 2025 and held it in 4 quarters.
VR Adviser's Septerna Inc position peaked at $17M in Q4 2025.
154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on VR Adviser's 13F filing for Q2 2026, filed 14 Aug 2026.