VA
SEPN

VR Adviser’s Septerna Inc SEPN Stock Holding History

VR Adviser’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$12.2M Sell
506,056
-104,752
-17% -$2.75M 0.45% 29
2025
Q4 		$17M Hold
610,808
– – 0.84% 23
2025
Q3 		$11.5M Buy
610,808
+70,355
+13% +$923K 0.65% 27
2025
Q2 		$5.71M Buy
+540,453
New +$4.45M 0.43% 26

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

VR Adviser's SEPN Position: Q1 2026 in Review

VR Adviser reduced its Septerna Inc (SEPN) stake by 17% in Q1 2026, selling an estimated $2.75M and leaving 506,056 shares worth $12.2M. The position accounts for 0.45% of the portfolio, ranked #29.

VR Adviser first reported a position in SEPN in Q2 2025 and has held it in 4 quarters since. The position peaked at $17M in Q4 2025. 124 funds tracked by Wall St. Rank hold SEPN as of Q1 2026.

  • VR Adviser held 506,056 shares of Septerna Inc worth $12.2M as of Q1 2026.
  • VR Adviser sold 104,752 Septerna Inc shares in Q1 2026, an estimated $2.75M.
  • Septerna Inc made up 0.45% of VR Adviser's portfolio in Q1 2026, its #29 holding.
  • VR Adviser first reported a position in Septerna Inc in Q2 2025 and has held it in 4 quarters since.
  • VR Adviser's Septerna Inc position peaked at $17M in Q4 2025.
  • 124 funds tracked by Wall St. Rank held Septerna Inc as of Q1 2026.

Based on VR Adviser's 13F filing for Q1 2026, filed 15 May 2026.