Fidelity Investments
SEPN

Fidelity Investments’s Septerna Inc SEPN Stock Holding History

Fidelity Investments’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$778K Sell
23,240
-206
-0.9% -$5.84K ﹤0.01% 3101
2026
Q1 		$563K Buy
23,446
+20,139
+609% +$529K ﹤0.01% 3083
2025
Q4 		$92.2K Sell
3,307
-131
-4% -$3.13K ﹤0.01% 3794
2025
Q3 		$64.7K Buy
3,438
+953
+38% +$12.5K ﹤0.01% 3851
2025
Q2 		$26.3K Sell
2,485
-47,293
-95% -$389K ﹤0.01% 4180
2025
Q1 		$288K Sell
49,778
-953,180
-95% -$10.9M ﹤0.01% 3113
2024
Q4 		$23M Buy
+1,002,958
New +$23.7M ﹤0.01% 1676

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Fidelity Investments's SEPN Position: Q2 2026 in Review

Fidelity Investments reduced its Septerna Inc (SEPN) stake by 0.88% in Q2 2026, selling an estimated $5.84K and leaving 23,240 shares worth $778K. The position accounts for ﹤0.01% of the portfolio, ranked #3101.

Fidelity Investments first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. The position peaked at $23M in Q4 2024. 153 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Fidelity Investments held 23,240 shares of Septerna Inc worth $778K as of Q2 2026.
  • Fidelity Investments sold 206 Septerna Inc shares in Q2 2026, an estimated $5.84K.
  • Septerna Inc made up ﹤0.01% of Fidelity Investments's portfolio in Q2 2026, its #3101 holding.
  • Fidelity Investments first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • Fidelity Investments's Septerna Inc position peaked at $23M in Q4 2024.
  • 153 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Fidelity Investments's 13F filing for Q2 2026, filed 13 Aug 2026.