Fidelity Investments
SEPN

Fidelity Investments’s Septerna Inc SEPN Stock Holding History

Fidelity Investments’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$563K Buy
23,446
+20,139
+609% +$529K ﹤0.01% 3083
2025
Q4 		$92.2K Sell
3,307
-131
-4% -$3.13K ﹤0.01% 3794
2025
Q3 		$64.7K Buy
3,438
+953
+38% +$12.5K ﹤0.01% 3851
2025
Q2 		$26.3K Sell
2,485
-47,293
-95% -$389K ﹤0.01% 4180
2025
Q1 		$288K Sell
49,778
-953,180
-95% -$10.9M ﹤0.01% 3113
2024
Q4 		$23M Buy
+1,002,958
New +$23.7M ﹤0.01% 1676

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Fidelity Investments's SEPN Position: Q1 2026 in Review

Fidelity Investments increased its Septerna Inc (SEPN) stake by 609% in Q1 2026, buying an estimated $529K and bringing the position to 23,446 shares worth $563K. The position accounts for ﹤0.01% of the portfolio, ranked #3083.

Fidelity Investments first reported a position in SEPN in Q4 2024 and has held it in 6 quarters since. The position peaked at $23M in Q4 2024. 124 funds tracked by Wall St. Rank hold SEPN as of Q1 2026.

  • Fidelity Investments held 23,446 shares of Septerna Inc worth $563K as of Q1 2026.
  • Fidelity Investments bought 20,139 Septerna Inc shares in Q1 2026, an estimated $529K.
  • Septerna Inc made up ﹤0.01% of Fidelity Investments's portfolio in Q1 2026, its #3083 holding.
  • Fidelity Investments first reported a position in Septerna Inc in Q4 2024 and has held it in 6 quarters since.
  • Fidelity Investments's Septerna Inc position peaked at $23M in Q4 2024.
  • 124 funds tracked by Wall St. Rank held Septerna Inc as of Q1 2026.

Based on Fidelity Investments's 13F filing for Q1 2026, filed 15 May 2026.