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SEPN

Nuveen’s Septerna Inc SEPN Stock Holding History

Nuveen’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$701K Buy
29,176
+3,378
+13% +$88.8K ﹤0.01% 2722
2025
Q4 		$719K Buy
25,798
+1,837
+8% +$43.9K ﹤0.01% 2745
2025
Q3 		$451K Sell
23,961
-34,010
-59% -$446K ﹤0.01% 2935
2025
Q2 		$613K Buy
57,971
+34,010
+142% +$280K ﹤0.01% 2810
2025
Q1 		$139K Hold
23,961
– – ﹤0.01% 3178
2024
Q4 		$549K Buy
+23,961
New +$567K ﹤0.01% 2953

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Nuveen's SEPN Position: Q1 2026 in Review

Nuveen increased its Septerna Inc (SEPN) stake by 13% in Q1 2026, buying an estimated $88.8K and bringing the position to 29,176 shares worth $701K. The position accounts for ﹤0.01% of the portfolio, ranked #2722.

Nuveen first reported a position in SEPN in Q4 2024 and has held it in 6 quarters since. The position peaked at $719K in Q4 2025. 124 funds tracked by Wall St. Rank hold SEPN as of Q1 2026.

  • Nuveen held 29,176 shares of Septerna Inc worth $701K as of Q1 2026.
  • Nuveen bought 3,378 Septerna Inc shares in Q1 2026, an estimated $88.8K.
  • Septerna Inc made up ﹤0.01% of Nuveen's portfolio in Q1 2026, its #2722 holding.
  • Nuveen first reported a position in Septerna Inc in Q4 2024 and has held it in 6 quarters since.
  • Nuveen's Septerna Inc position peaked at $719K in Q4 2025.
  • 124 funds tracked by Wall St. Rank held Septerna Inc as of Q1 2026.

Based on Nuveen's 13F filing for Q1 2026, filed 30 Apr 2026.