Invesco
SEPN

Invesco’s Septerna Inc SEPN Stock Holding History

Invesco’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$807K Sell
24,094
-58,774
-71% -$1.67M ﹤0.01% 3029
2026
Q1 		$1.99M Sell
82,868
-79,146
-49% -$2.08M ﹤0.01% 2544
2025
Q4 		$4.52M Sell
162,014
-15,056
-9% -$360K ﹤0.01% 2289
2025
Q3 		$3.33M Buy
177,070
+165,237
+1,396% +$2.17M ﹤0.01% 2408
2025
Q2 		$125K Sell
11,833
-369
-3% -$3.04K ﹤0.01% 3619
2025
Q1 		$70.6K Buy
12,202
+48
+0.4% +$548 ﹤0.01% 3671
2024
Q4 		$278K Buy
+12,154
New +$287K ﹤0.01% 3434

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Invesco's SEPN Position: Q2 2026 in Review

Invesco reduced its Septerna Inc (SEPN) stake by 71% in Q2 2026, selling an estimated $1.67M and leaving 24,094 shares worth $807K. The position accounts for ﹤0.01% of the portfolio, ranked #3029.

Invesco first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. The position peaked at $4.52M in Q4 2025. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Invesco held 24,094 shares of Septerna Inc worth $807K as of Q2 2026.
  • Invesco sold 58,774 Septerna Inc shares in Q2 2026, an estimated $1.67M.
  • Septerna Inc made up ﹤0.01% of Invesco's portfolio in Q2 2026, its #3029 holding.
  • Invesco first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • Invesco's Septerna Inc position peaked at $4.52M in Q4 2025.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Invesco's 13F filing for Q2 2026, filed 14 Aug 2026.