Invesco
SEPN

Invesco’s Septerna Inc SEPN Stock Holding History

Invesco’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.99M Sell
82,868
-79,146
-49% -$2.08M ﹤0.01% 2544
2025
Q4 		$4.52M Sell
162,014
-15,056
-9% -$360K ﹤0.01% 2289
2025
Q3 		$3.33M Buy
177,070
+165,237
+1,396% +$2.17M ﹤0.01% 2408
2025
Q2 		$125K Sell
11,833
-369
-3% -$3.04K ﹤0.01% 3619
2025
Q1 		$70.6K Buy
12,202
+48
+0.4% +$548 ﹤0.01% 3671
2024
Q4 		$278K Buy
+12,154
New +$287K ﹤0.01% 3434

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Invesco's SEPN Position: Q1 2026 in Review

Invesco reduced its Septerna Inc (SEPN) stake by 49% in Q1 2026, selling an estimated $2.08M and leaving 82,868 shares worth $1.99M. The position accounts for ﹤0.01% of the portfolio, ranked #2544.

Invesco first reported a position in SEPN in Q4 2024 and has held it in 6 quarters since. The position peaked at $4.52M in Q4 2025. 124 funds tracked by Wall St. Rank hold SEPN as of Q1 2026.

  • Invesco held 82,868 shares of Septerna Inc worth $1.99M as of Q1 2026.
  • Invesco sold 79,146 Septerna Inc shares in Q1 2026, an estimated $2.08M.
  • Septerna Inc made up ﹤0.01% of Invesco's portfolio in Q1 2026, its #2544 holding.
  • Invesco first reported a position in Septerna Inc in Q4 2024 and has held it in 6 quarters since.
  • Invesco's Septerna Inc position peaked at $4.52M in Q4 2025.
  • 124 funds tracked by Wall St. Rank held Septerna Inc as of Q1 2026.

Based on Invesco's 13F filing for Q1 2026, filed 12 May 2026.