Northern Trust
SEPN

Northern Trust’s Septerna Inc SEPN Stock Holding History

Northern Trust’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$3.95M Buy
164,530
+10,334
+7% +$272K ﹤0.01% 2589
2025
Q4 		$4.3M Sell
154,196
-13,149
-8% -$314K ﹤0.01% 2561
2025
Q3 		$3.15M Buy
167,345
+13,001
+8% +$171K ﹤0.01% 2769
2025
Q2 		$1.63M Sell
154,344
-3,696
-2% -$30.4K ﹤0.01% 3105
2025
Q1 		$915K Buy
158,040
+10,264
+7% +$117K ﹤0.01% 3324
2024
Q4 		$3.38M Buy
+147,776
New +$3.49M ﹤0.01% 2741

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Northern Trust's SEPN Position: Q1 2026 in Review

Northern Trust increased its Septerna Inc (SEPN) stake by 6.7% in Q1 2026, buying an estimated $272K and bringing the position to 164,530 shares worth $3.95M. The position accounts for ﹤0.01% of the portfolio, ranked #2589.

Northern Trust first reported a position in SEPN in Q4 2024 and has held it in 6 quarters since. The position peaked at $4.3M in Q4 2025. 124 funds tracked by Wall St. Rank hold SEPN as of Q1 2026.

  • Northern Trust held 164,530 shares of Septerna Inc worth $3.95M as of Q1 2026.
  • Northern Trust bought 10,334 Septerna Inc shares in Q1 2026, an estimated $272K.
  • Septerna Inc made up ﹤0.01% of Northern Trust's portfolio in Q1 2026, its #2589 holding.
  • Northern Trust first reported a position in Septerna Inc in Q4 2024 and has held it in 6 quarters since.
  • Northern Trust's Septerna Inc position peaked at $4.3M in Q4 2025.
  • 124 funds tracked by Wall St. Rank held Septerna Inc as of Q1 2026.

Based on Northern Trust's 13F filing for Q1 2026, filed 14 May 2026.