Northern Trust
SEPN

Northern Trust’s Septerna Inc SEPN Stock Holding History

Northern Trust’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$6.74M Buy
201,131
+36,601
+22% +$1.04M ﹤0.01% 2441
2026
Q1 		$3.95M Buy
164,530
+10,334
+7% +$272K ﹤0.01% 2589
2025
Q4 		$4.3M Sell
154,196
-13,149
-8% -$314K ﹤0.01% 2561
2025
Q3 		$3.15M Buy
167,345
+13,001
+8% +$171K ﹤0.01% 2769
2025
Q2 		$1.63M Sell
154,344
-3,696
-2% -$30.4K ﹤0.01% 3105
2025
Q1 		$915K Buy
158,040
+10,264
+7% +$117K ﹤0.01% 3324
2024
Q4 		$3.38M Buy
+147,776
New +$3.49M ﹤0.01% 2741

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Northern Trust's SEPN Position: Q2 2026 in Review

Northern Trust increased its Septerna Inc (SEPN) stake by 22% in Q2 2026, buying an estimated $1.04M and bringing the position to 201,131 shares worth $6.74M. The position accounts for ﹤0.01% of the portfolio, ranked #2441.

Northern Trust first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Northern Trust held 201,131 shares of Septerna Inc worth $6.74M as of Q2 2026.
  • Northern Trust bought 36,601 Septerna Inc shares in Q2 2026, an estimated $1.04M.
  • Septerna Inc made up ﹤0.01% of Northern Trust's portfolio in Q2 2026, its #2441 holding.
  • Northern Trust first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Northern Trust's 13F filing for Q2 2026, filed 13 Aug 2026.