Barclays
SEPN icon

Barclays’s Septerna Inc SEPN Stock Holding History

Barclays’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q3 		$1.94M Sell
49,614
-207
-0.4% -$7.85K ﹤0.01% 2618
2026
Q2 		$1.67M Buy
49,821
+27,107
+119% +$769K ﹤0.01% 2452
2026
Q1 		$546K Sell
22,714
-15,433
-40% -$406K ﹤0.01% 3148
2025
Q4 		$1.06M Buy
38,147
+8,045
+27% +$192K ﹤0.01% 3389
2025
Q3 		$566K Sell
30,102
-5,604
-16% -$73.5K ﹤0.01% 3729
2025
Q2 		$377K Buy
35,706
+12,973
+57% +$107K ﹤0.01% 3916
2025
Q1 		$132K Sell
22,733
-6,052
-21% -$69.1K ﹤0.01% 4290
2024
Q4 		$659K Buy
+28,785
New +$681K ﹤0.01% 3653

Other funds holding SEPN

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.32T AUM 44.66% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.44T AUM 36.12% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.92T AUM 36.1% 1-Year Est. Return
Loomis, Sayles & Company
Loomis, Sayles & Company Boston, Massachusetts $77.1B AUM 11.99% 1-Year Est. Return
Universal-Beteiligungs- und Servicegesellschaft
Universal-Beteiligungs- und Servicegesellschaft Frankfurt Am Main, Germany $65.3B AUM 33.78% 1-Year Est. Return
Nuveen
Nuveen Charlotte, North Carolina $420B AUM 34.97% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $765B AUM 28.39% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $551B AUM 33.95% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $71.4B AUM 33.43% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.84T AUM 33.86% 1-Year Est. Return

Barclays's SEPN Position: Q3 2026 in Review

Barclays reduced its Septerna Inc (SEPN) stake by 0.42% in Q3 2026, selling an estimated $7.85K and leaving 49,614 shares worth $1.94M. The position accounts for ﹤0.01% of the portfolio, ranked #2618.

Barclays first reported a position in SEPN in Q4 2024 and has held it in 8 quarters since. 70 funds tracked by Wall St. Rank hold SEPN as of Q3 2026.

  • Barclays held 49,614 shares of Septerna Inc worth $1.94M as of Q3 2026.
  • Barclays sold 207 Septerna Inc shares in Q3 2026, an estimated $7.85K.
  • Septerna Inc made up ﹤0.01% of Barclays's portfolio in Q3 2026, its #2618 holding.
  • Barclays first reported a position in Septerna Inc in Q4 2024 and has held it in 8 quarters since.
  • 70 funds tracked by Wall St. Rank held Septerna Inc as of Q3 2026.

Based on Barclays's 13F filing for Q3 2026, filed 6 Nov 2026.