Barclays
SEPN

Barclays’s Septerna Inc SEPN Stock Holding History

Barclays’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$1.67M Buy
49,821
+27,107
+119% +$769K ﹤0.01% 2452
2026
Q1 		$546K Sell
22,714
-15,433
-40% -$406K ﹤0.01% 3149
2025
Q4 		$1.06M Buy
38,147
+8,045
+27% +$192K ﹤0.01% 3389
2025
Q3 		$566K Sell
30,102
-5,604
-16% -$73.5K ﹤0.01% 3729
2025
Q2 		$377K Buy
35,706
+12,973
+57% +$107K ﹤0.01% 3916
2025
Q1 		$132K Sell
22,733
-6,052
-21% -$69.1K ﹤0.01% 4290
2024
Q4 		$659K Buy
+28,785
New +$681K ﹤0.01% 3653

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Barclays's SEPN Position: Q2 2026 in Review

Barclays increased its Septerna Inc (SEPN) stake by 119% in Q2 2026, buying an estimated $769K and bringing the position to 49,821 shares worth $1.67M. The position accounts for ﹤0.01% of the portfolio, ranked #2452.

Barclays first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. 153 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Barclays held 49,821 shares of Septerna Inc worth $1.67M as of Q2 2026.
  • Barclays bought 27,107 Septerna Inc shares in Q2 2026, an estimated $769K.
  • Septerna Inc made up ﹤0.01% of Barclays's portfolio in Q2 2026, its #2452 holding.
  • Barclays first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • 153 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Barclays's 13F filing for Q2 2026, filed 14 Aug 2026.