Geode Capital Management
SEPN

Geode Capital Management’s Septerna Inc SEPN Stock Holding History

Geode Capital Management’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$22.8M Buy
679,163
+34,017
+5% +$965K ﹤0.01% 2075
2026
Q1 		$15.5M Buy
645,146
+72,412
+13% +$1.9M ﹤0.01% 2139
2025
Q4 		$16M Buy
572,734
+27,033
+5% +$646K ﹤0.01% 2134
2025
Q3 		$10.3M Buy
545,701
+57,745
+12% +$758K ﹤0.01% 2400
2025
Q2 		$5.16M Buy
487,956
+78,316
+19% +$645K ﹤0.01% 2711
2025
Q1 		$2.37M Buy
409,640
+29,063
+8% +$332K ﹤0.01% 2971
2024
Q4 		$8.72M Buy
+380,577
New +$9M ﹤0.01% 2456

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Geode Capital Management's SEPN Position: Q2 2026 in Review

Geode Capital Management increased its Septerna Inc (SEPN) stake by 5.3% in Q2 2026, buying an estimated $965K and bringing the position to 679,163 shares worth $22.8M. The position accounts for ﹤0.01% of the portfolio, ranked #2075.

Geode Capital Management first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Geode Capital Management held 679,163 shares of Septerna Inc worth $22.8M as of Q2 2026.
  • Geode Capital Management bought 34,017 Septerna Inc shares in Q2 2026, an estimated $965K.
  • Septerna Inc made up ﹤0.01% of Geode Capital Management's portfolio in Q2 2026, its #2075 holding.
  • Geode Capital Management first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Geode Capital Management's 13F filing for Q2 2026, filed 12 Aug 2026.