American Century Companies’s Septerna Inc SEPN Stock Holding History

American Century Companies’s Portfolio SEPN Stock Details SEPN Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$2.04M	Sell	60,973 -317	-0.5%	-$8.99K	﹤0.01%	2193
2026 Q1	$1.47M	Buy	61,290 +10,601	+21%	+$279K	﹤0.01%	2217
2025 Q4	$1.41M	Buy	50,689 +25,406	+100%	+$607K	﹤0.01%	2216
2025 Q3	$476K	Buy	+25,283	New	+$332K	﹤0.01%	2520

Other funds holding SEPN

RCM

RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return

TGV

TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

TGV

TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return

Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return

Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

Jupiter Topco New York $245B AUM

American Century Companies's SEPN Position: Q2 2026 in Review

American Century Companies reduced its Septerna Inc (SEPN) stake by 0.52% in Q2 2026, selling an estimated $8.99K and leaving 60,973 shares worth $2.04M. The position accounts for ﹤0.01% of the portfolio, ranked #2193.

American Century Companies first reported a position in SEPN in Q3 2025 and has held it in 4 quarters since. 153 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

American Century Companies held 60,973 shares of Septerna Inc worth $2.04M as of Q2 2026.
American Century Companies sold 317 Septerna Inc shares in Q2 2026, an estimated $8.99K.
Septerna Inc made up ﹤0.01% of American Century Companies's portfolio in Q2 2026, its #2193 holding.
American Century Companies first reported a position in Septerna Inc in Q3 2025 and has held it in 4 quarters since.
153 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on American Century Companies's 13F filing for Q2 2026, filed 12 Aug 2026.