BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-9.76%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$16.2B
AUM Growth
+$16.2B
Cap. Flow
+$164M
Cap. Flow %
1.01%
Top 10 Hldgs %
86.32%
Holding
116
New
17
Increased
25
Reduced
19
Closed
6

Top Buys

1
ALXN
Alexion Pharmaceuticals Inc
ALXN
$45.1M
2
ACAD icon
Acadia Pharmaceuticals
ACAD
$44.4M
3
KOD icon
Kodiak Sciences
KOD
$25.1M
4
MDGL icon
Madrigal Pharmaceuticals
MDGL
$22M
5
ALLK
Allakos
ALLK
$17.6M

Top Sells

1
BOLD
Audentes Therapeutics, Inc
BOLD
$48.2M
2
EXAS icon
Exact Sciences
EXAS
$42.9M
3
BLCM
Bellicum Pharmaceuticals, Inc.
BLCM
$11.4M
4
ADPT icon
Adaptive Biotechnologies
ADPT
$10.3M
5
NXTC icon
NextCure
NXTC
$8.45M

Sector Composition

1 Healthcare 98.59%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
RETA
51
DELISTED
Reata Pharmaceuticals, Inc. Class A Common Stock
RETA
$8.08M 0.05% 55,983 +15,000 +37% +$2.17M
SYRE icon
52
Spyre Therapeutics
SYRE
$996M
$7.99M 0.05% 1,713,604 – –
IFRX icon
53
InflaRx
IFRX
$108M
$6.79M 0.04% 1,778,415 – –
ALEC icon
54
Alector
ALEC
$238M
$6.76M 0.04% +280,000 New +$6.76M
SGMO icon
55
Sangamo Therapeutics
SGMO
$157M
$6.37M 0.04% 999,823 – –
BDSI
56
DELISTED
BioDelivery Sciences International, Inc.
BDSI
$6.21M 0.04% +1,638,334 New +$6.21M
FLGT icon
57
Fulgent Genetics
FLGT
$679M
$6.13M 0.04% 569,444 – –
ACGN
58
DELISTED
Aceragen, Inc. Common Stock
ACGN
$6.08M 0.04% 4,608,786 – –
ALBO
59
DELISTED
Albireo Pharma, Inc. Common Stock
ALBO
$6.04M 0.04% 369,047 +119,047 +48% +$1.95M
HZNP
60
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$5.92M 0.04% +200,000 New +$5.92M
HOOK
61
DELISTED
HOOKIPA Pharma
HOOK
$5.78M 0.04% 700,481 -192,376 -22% -$1.59M
ISEE
62
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$5.63M 0.03% 1,635,501 +1,493,751 +1,054% +$5.14M
CABA icon
63
Cabaletta Bio
CABA
$133M
$4.65M 0.03% 636,363 – –
TARA icon
64
Protara Therapeutics
TARA
$120M
$4.59M 0.03% +199,671 New +$4.59M
TPST icon
65
Tempest Therapeutics
TPST
$44M
$4.4M 0.03% 833,333 – –
PASG icon
66
Passage Bio
PASG
$22.7M
$4.33M 0.03% +275,000 New +$4.33M
CNST
67
DELISTED
Constellation Pharmaceuticals, Inc.
CNST
$4.19M 0.03% 133,333 – –
IMMU
68
DELISTED
Immunomedics Inc
IMMU
$4.18M 0.03% +310,000 New +$4.18M
NERV icon
69
Minerva Neurosciences
NERV
$16.5M
$4.15M 0.03% +688,531 New +$4.15M
SYRS
70
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
$4.09M 0.03% 690,167 – –
CPRX icon
71
Catalyst Pharmaceutical
CPRX
$2.52B
$4.08M 0.03% 1,060,714 -281,188 -21% -$1.08M
ABEO icon
72
Abeona Therapeutics
ABEO
$350M
$3.34M 0.02% 1,590,686 -697,549 -30% -$1.46M
ANAB icon
73
AnaptysBio
ANAB
$569M
$3.32M 0.02% 234,592 +121,506 +107% +$1.72M
EVFM
74
DELISTED
Evofem Biosciences, Inc. Common Stock
EVFM
$3.31M 0.02% 621,297 -135,516 -18% -$721K
MTEM
75
DELISTED
Molecular Templates, Inc.
MTEM
$3.16M 0.02% 237,917 -78,813 -25% -$1.05M
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