BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+28.43%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$15.2B
AUM Growth
+$15.2B
Cap. Flow
-$49.8M
Cap. Flow %
-0.33%
Top 10 Hldgs %
84.66%
Holding
127
New
12
Increased
13
Reduced
22
Closed
28

Top Buys

1
AMRN
Amarin Corp
AMRN
$185M
2
PRNB
Principia Biopharma Inc. Common Stock
PRNB
$52.2M
3
ACAD icon
Acadia Pharmaceuticals
ACAD
$25.1M
4
INSM icon
Insmed
INSM
$23.3M
5
GWPH
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$12.9M

Top Sells

1
ACGN
Aceragen, Inc. Common Stock
ACGN
$301M
2
BLUE
bluebird bio
BLUE
$20.5M
3
PHXM
PHAXIAM Therapeutics S.A.. American Depositary Shares
PHXM
$17.1M
4
HALO icon
Halozyme
HALO
$15.2M
5
EXEL icon
Exelixis
EXEL
$11M

Sector Composition

1 Healthcare 91.43%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$3.94B 25.93% 51,046,060 – –
INCY icon
2
Incyte
INCY
$16.5B
$2.37B 15.59% 34,251,309 +275 +0% +$19K
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$2.06B 13.57% 11,959,824 – –
ALXN
4
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$1.19B 7.83% 8,555,894 – –
GHDX
5
DELISTED
Genomic Health, Inc.
GHDX
$968M 6.38% 13,790,970 +396 +0% +$27.8K
BMRN icon
6
BioMarin Pharmaceuticals
BMRN
$11.2B
$735M 4.84% 7,583,084 – –
ACAD icon
7
Acadia Pharmaceuticals
ACAD
$4.38B
$590M 3.89% 28,439,114 +1,210,776 +4% +$25.1M
AMRN
8
Amarin Corp
AMRN
$311M
$554M 3.65% 34,069,509 +11,400,000 +50% +$185M
MDGL icon
9
Madrigal Pharmaceuticals
MDGL
$9.76B
$250M 1.65% 1,169,278 – –
ASND icon
10
Ascendis Pharma
ASND
$11.8B
$201M 1.32% 2,837,352 – –
HRTX icon
11
Heron Therapeutics
HRTX
$207M
$159M 1.05% 5,025,298 – –
NVTA
12
DELISTED
Invitae Corporation
NVTA
$141M 0.93% 8,399,411 – –
DBVT
13
DBV Technologies
DBVT
$264M
$124M 0.82% 5,509,560 – –
MRTX
14
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$118M 0.78% 2,513,462 – –
NBIX icon
15
Neurocrine Biosciences
NBIX
$13.8B
$116M 0.77% 944,624 – –
BCRX icon
16
BioCryst Pharmaceuticals
BCRX
$1.74B
$115M 0.76% 15,103,081 +1,090,909 +8% +$8.32M
ARRY
17
DELISTED
Array Biopharma Inc
ARRY
$86M 0.57% 5,656,196 – –
SAGE
18
DELISTED
Sage Therapeutics
SAGE
$80.2M 0.53% 567,497 -45,803 -7% -$6.47M
RYTM icon
19
Rhythm Pharmaceuticals
RYTM
$6.85B
$79M 0.52% 2,708,200 – –
CERS icon
20
Cerus
CERS
$251M
$77.5M 0.51% 10,749,937 – –
ARGX icon
21
argenx
ARGX
$43.6B
$77.3M 0.51% 1,019,557 +57,803 +6% +$4.38M
KNSA icon
22
Kiniksa Pharmaceuticals
KNSA
$2.48B
$76.5M 0.5% 3,000,000 – –
ONCE
23
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$75.5M 0.5% 1,384,130 – –
GWPH
24
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$68.5M 0.45% 396,700 +74,900 +23% +$12.9M
CBAY
25
DELISTED
Cymabay Therapeutics
CBAY
$54.5M 0.36% 4,917,700 – –
1
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