BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-2.68%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$17.3B
AUM Growth
+$17.3B
Cap. Flow
-$421M
Cap. Flow %
-2.43%
Top 10 Hldgs %
87.61%
Holding
112
New
6
Increased
20
Reduced
13
Closed
5

Top Buys

1
ROIV icon
Roivant Sciences
ROIV
$46.9M
2
ABCL icon
AbCellera Biologics
ABCL
$38.8M
3
KYMR icon
Kymera Therapeutics
KYMR
$34.4M
4
IMGN
Immunogen Inc
IMGN
$28.7M
5
ACAD icon
Acadia Pharmaceuticals
ACAD
$22.2M

Top Sells

1
SGEN
Seagen Inc. Common Stock
SGEN
$454M
2
VSTM icon
Verastem
VSTM
$180M
3
LPTX icon
Leap Therapeutics
LPTX
$19.6M
4
KRYS icon
Krystal Biotech
KRYS
$15.6M
5
BPMC
Blueprint Medicines
BPMC
$15M

Sector Composition

1 Healthcare 99.16%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$8.57B 49.63% 44,554,162 -2,359,607 -5% -$454M
INCY icon
2
Incyte
INCY
$16.5B
$2.25B 13.03% 36,178,056 +2,656 +0% +$165K
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$2.08B 12.04% 11,668,897 – –
ACAD icon
4
Acadia Pharmaceuticals
ACAD
$4.38B
$1.03B 5.94% 42,864,612 +926,126 +2% +$22.2M
MDGL icon
5
Madrigal Pharmaceuticals
MDGL
$9.76B
$357M 2.07% 1,545,113 – –
BMRN icon
6
BioMarin Pharmaceuticals
BMRN
$11.2B
$330M 1.91% 3,810,248 – –
IMCR icon
7
Immunocore
IMCR
$1.62B
$151M 0.87% 2,520,731 – –
KOD icon
8
Kodiak Sciences
KOD
$478M
$119M 0.69% 17,310,490 – –
AKRO icon
9
Akero Therapeutics
AKRO
$3.74B
$111M 0.64% 2,368,378 – –
ARGX icon
10
argenx
ARGX
$43.6B
$109M 0.63% 280,159 – –
RYTM icon
11
Rhythm Pharmaceuticals
RYTM
$6.85B
$107M 0.62% 6,498,267 – –
REPL icon
12
Replimune Group
REPL
$422M
$106M 0.62% 4,578,280 – –
ABCL icon
13
AbCellera Biologics
ABCL
$1.25B
$106M 0.62% 16,450,180 +6,000,000 +57% +$38.8M
KYMR icon
14
Kymera Therapeutics
KYMR
$2.95B
$101M 0.58% 4,375,340 +1,495,515 +52% +$34.4M
ROIV icon
15
Roivant Sciences
ROIV
$8.15B
$95M 0.55% 9,428,592 +4,651,162 +97% +$46.9M
BCRX icon
16
BioCryst Pharmaceuticals
BCRX
$1.74B
$89.5M 0.52% 12,710,818 – –
SWTX
17
DELISTED
SpringWorks Therapeutics
SWTX
$78.7M 0.46% 2,999,846 +246,344 +9% +$6.46M
TRDA icon
18
Entrada Therapeutics
TRDA
$208M
$73.7M 0.43% 4,865,819 – –
RVMD icon
19
Revolution Medicines
RVMD
$7.1B
$72M 0.42% 2,691,493 – –
IMTX icon
20
Immatics
IMTX
$619M
$65.1M 0.38% 5,640,816 +453,735 +9% +$5.24M
KDNY
21
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
$55.9M 0.32% 1,455,202 – –
MRTX
22
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$50.9M 0.29% 1,409,784 – –
DICE
23
DELISTED
DICE Therapeutics, Inc. Common Stock
DICE
$48.1M 0.28% 1,035,786 – –
BMEA icon
24
Biomea Fusion
BMEA
$116M
$46.3M 0.27% 2,108,949 – –
PRLD icon
25
Prelude Therapeutics
PRLD
$68.5M
$45.6M 0.26% 10,123,824 – –
1
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