BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+25.41%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$16.7B
AUM Growth
+$16.7B
Cap. Flow
-$302M
Cap. Flow %
-1.81%
Top 10 Hldgs %
86.98%
Holding
128
New
13
Increased
17
Reduced
8
Closed
15

Top Buys

1
SWTX
SpringWorks Therapeutics
SWTX
$39.8M
2
PRME icon
Prime Medicine
PRME
$19.1M
3
REPL icon
Replimune Group
REPL
$18.6M
4
SPRY icon
ARS Pharmaceuticals
SPRY
$17.1M
5
DNLI icon
Denali Therapeutics
DNLI
$13.9M

Top Sells

1
GBT
Global Blood Therapeutics, Inc.
GBT
$254M
2
CCXI
ChemoCentryx, Inc.
CCXI
$92.6M
3
TVTX icon
Travere Therapeutics
TVTX
$43.6M
4
FMTX
Forma Therapeutics Holdings, Inc. Common Stock
FMTX
$37.6M
5
ALT icon
Altimmune
ALT
$18.4M

Sector Composition

1 Healthcare 99.74%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$6.03B 36.21% 46,912,266 – –
INCY icon
2
Incyte
INCY
$16.5B
$2.9B 17.44% 36,154,971 +397 +0% +$31.9K
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$2.57B 15.41% 11,668,897 – –
BMRN icon
4
BioMarin Pharmaceuticals
BMRN
$11.2B
$789M 4.74% 7,620,494 – –
ACAD icon
5
Acadia Pharmaceuticals
ACAD
$4.38B
$667M 4.01% 41,923,486 – –
ASND icon
6
Ascendis Pharma
ASND
$11.8B
$605M 3.63% 4,954,855 +102,200 +2% +$12.5M
MDGL icon
7
Madrigal Pharmaceuticals
MDGL
$9.76B
$448M 2.69% 1,545,113 +45,900 +3% +$13.3M
RYTM icon
8
Rhythm Pharmaceuticals
RYTM
$6.85B
$185M 1.11% 6,354,608 +291,906 +5% +$8.5M
BCRX icon
9
BioCryst Pharmaceuticals
BCRX
$1.74B
$146M 0.88% 12,710,818 – –
IMCR icon
10
Immunocore
IMCR
$1.62B
$144M 0.86% 2,520,731 – –
AKRO icon
11
Akero Therapeutics
AKRO
$3.74B
$130M 0.78% 2,368,378 – –
REPL icon
12
Replimune Group
REPL
$422M
$125M 0.75% 4,578,280 +684,437 +18% +$18.6M
KOD icon
13
Kodiak Sciences
KOD
$478M
$124M 0.74% 17,310,490 – –
HZNP
14
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$110M 0.66% 969,727 – –
ARGX icon
15
argenx
ARGX
$43.6B
$106M 0.64% 280,159 – –
ABCL icon
16
AbCellera Biologics
ABCL
$1.25B
$106M 0.64% 10,450,180 – –
KYMR icon
17
Kymera Therapeutics
KYMR
$2.95B
$71.9M 0.43% 2,879,825 – –
KDNY
18
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
$66.4M 0.4% 2,534,102 – –
TRDA icon
19
Entrada Therapeutics
TRDA
$208M
$65.8M 0.4% 4,865,819 – –
MRTX
20
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$63.9M 0.38% 1,409,784 – –
PRLD icon
21
Prelude Therapeutics
PRLD
$68.5M
$61.1M 0.37% 10,123,824 – –
CERS icon
22
Cerus
CERS
$251M
$58.6M 0.35% 16,067,558 – –
JBIO
23
Jade Biosciences, Inc. Common Stock
JBIO
$258M
$57.9M 0.35% 1,976,868 -2,700 -0.1% -$79.1K
IGMS
24
DELISTED
IGM Biosciences
IGMS
$53.7M 0.32% 3,156,102 – –
IMTX icon
25
Immatics
IMTX
$619M
$45.2M 0.27% 5,187,081 +763,350 +17% +$6.65M
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