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Baker Bros. Advisors’s Prime Medicine PRME Stock Holding History

Baker Bros. Advisors’s Portfolio PRME Stock Details PRME Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q2 		– Sell
-1,028,466
Closed -$2.05M – 96
2025
Q1 		$2.05M Hold
1,028,466
– – 0.02% 76
2024
Q4 		$3M Hold
1,028,466
– – 0.03% 79
2024
Q3 		$3.98M Hold
1,028,466
– – 0.04% 71
2024
Q2 		$5.29M Hold
1,028,466
– – 0.07% 64
2024
Q1 		$7.2M Hold
1,028,466
– – 0.09% 58
2023
Q4 		$9.11M Hold
1,028,466
– – 0.1% 49
2023
Q3 		$9.81M Hold
1,028,466
– – 0.06% 43
2023
Q2 		$15.1M Hold
1,028,466
– – 0.09% 47
2023
Q1 		$12.7M Hold
1,028,466
– – 0.07% 46
2022
Q4 		$19.1M Buy
+1,028,466
New +$18.6M 0.11% 44

Other funds holding PRME

AI
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T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
AIM
ARK Investment Management St. Petersburg, Florida $12.9B AUM 64.92% 1-Year Est. Return
RG
Redmile Group San Francisco, California $1.51B AUM 164.17% 1-Year Est. Return
MM
MWG Management Road Town, Tortola, British Virgin Islands $81.3M AUM 2.28% 1-Year Est. Return
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group Minato-Ku, Tokyo, Japan $154B AUM 29.96% 1-Year Est. Return
NAMA
Nikko Asset Management Americas New York $7.07B AUM 50.91% 1-Year Est. Return

Baker Bros. Advisors's PRME Position: Q2 2025 in Review

Baker Bros. Advisors sold out of Prime Medicine (PRME) in Q2 2025, closing a stake of 1,028,466 shares — an estimated $2.05M sold.

Baker Bros. Advisors first reported a position in PRME in Q4 2022 and held it in 10 quarters. The position peaked at $19.1M in Q4 2022. 121 funds tracked by Wall St. Rank hold PRME as of Q2 2025.

  • Baker Bros. Advisors reported no remaining Prime Medicine position as of Q2 2025 after selling out during the quarter.
  • Baker Bros. Advisors sold 1,028,466 Prime Medicine shares in Q2 2025, an estimated $2.05M.
  • Baker Bros. Advisors first reported a position in Prime Medicine in Q4 2022 and held it in 10 quarters.
  • Baker Bros. Advisors's Prime Medicine position peaked at $19.1M in Q4 2022.
  • 121 funds tracked by Wall St. Rank held Prime Medicine as of Q2 2025.

Based on Baker Bros. Advisors's 13F filing for Q2 2025, filed 14 Aug 2025.