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Prime Medicine
PRME

Overview Fund Activity

119 hedge funds and large institutions have $144M invested in Prime Medicine in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 36 increasing their positions, 34 reducing their positions, and 32 closing their positions.

Holders
119
Holders Change
-4
Holders Change %
-3.25%
% of All Funds
1.6%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
29
Increased
36
Reduced
34
Closed
32
Calls
$1.21M
Puts
$1.12M
Net Calls
+$96K
Net Calls Change
+$213K

Top Buyers

1
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$16M
2
CC
2
Casdin Capital
New York
$3.87M
3
SSA
3
Schonfeld Strategic Advisors
New York
$2.02M
4
Citadel Advisors
4
Citadel Advisors
Florida
$1.29M
5
FAM
5
Fred Alger Management
New York
$946K

Top Sellers

1
Millennium Management
1
Millennium Management
New York
$366K
2
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$162K
3
Sumitomo Mitsui Trust Group
3
Sumitomo Mitsui Trust Group
Japan
$3.94M
4
NAMA
4
Nikko Asset Management Americas
New York
$3.89M
5
BBA
5
Baker Bros. Advisors
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
AI
1
Alphabet Inc
California
$37.2M 15,062,498 – –
T. Rowe Price Investment Management
2
T. Rowe Price Investment Management
Maryland
$16M 6,484,787 +2,341,691 +57%
BlackRock
3
BlackRock
New York
$11.1M 4,485,828 +179,617 +4%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$9.25M 3,744,427 -2,808 -0.1%
Vanguard Group
5
Vanguard Group
Pennsylvania
$8.96M 3,627,510 -13,838 -0.4%
AIM
6
ARK Investment Management
Florida
$5.74M 2,322,669 -772,503 -25%
RG
7
Redmile Group
California
$5.12M 2,074,350 – –
MM
8
MWG Management
British Virgin Islands
$4.43M 1,792,210 – –
Sumitomo Mitsui Trust Group
9
Sumitomo Mitsui Trust Group
Japan
$3.94M 1,594,518 -1,331,505 -46%
NAMA
10
Nikko Asset Management Americas
New York
$3.89M 1,589,117 -1,336,906 -46%
CC
11
Casdin Capital
New York
$3.87M 1,567,175 +1,200,000 +327%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$3.73M 1,510,749 -15,781 -1%
State Street
13
State Street
Massachusetts
$3.06M 1,239,337 +94,032 +8%
GWM
14
Greenwich Wealth Management
Connecticut
$2.09M 846,201 +27,200 +3%
SSA
15
Schonfeld Strategic Advisors
New York
$2.02M 818,518 +818,518 New
FCM
16
Farallon Capital Management
California
$1.85M 750,000 – –
Morgan Stanley
17
Morgan Stanley
New York
$1.45M 587,676 +232,500 +65%
Citadel Advisors
18
Citadel Advisors
Florida
$1.29M 521,508 +521,508 New
Charles Schwab
19
Charles Schwab
California
$1.28M 518,628 +14,931 +3%
Northern Trust
20
Northern Trust
Illinois
$1.27M 512,234 -15,075 -3%
MCM
21
Moore Capital Management
New York
$1.24M 500,000 – –
AQR Capital Management
22
AQR Capital Management
Connecticut
$1.05M 424,355 +180,560 +74%
FAM
23
Fred Alger Management
New York
$946K 383,194 +383,194 New
BG
24
Bollard Group
Massachusetts
$892K 361,136 – –
Two Sigma Investments
25
Two Sigma Investments
New York
$638K 258,423 -347 -0.1%
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