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Prime Medicine
PRME

83 hedge funds and large institutions have $472M invested in Prime Medicine in 2023 Q3 according to their latest regulatory filings, with 11 funds opening new positions, 35 increasing their positions, 15 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

870% more call options, than puts

Call options by funds: $97K | Put options by funds: $10K

133% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 15

83% more first-time investments, than exits

New positions opened: 11 | Existing positions closed: 6

5% more funds holding

Funds holding: 79 → 83 (+4)

3.45% more ownership

Funds ownership: 47.45% → 50.89% (+3.4%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

30% less capital invested

Capital invested by funds: $676M → $472M (-$203M)

Holders
83
Holders Change
+4
Holders Change %
+5.06%
% of All Funds
1.32%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
11
Increased
35
Reduced
15
Closed
6
Calls
$97K
Puts
$10K
Net Calls
+$87K
Net Calls Change
+$87K

Top Buyers

Rank Fund Capital Flow
1
State Street
State Street
Massachusetts
+$14M
2
Vanguard Group
Vanguard Group
Pennsylvania
+$8.02M
3
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group
Japan
+$7.42M
4
NAMA
Nikko Asset Management Americas
New York
+$7.41M
5
BlackRock
BlackRock
New York
+$5.78M

Top Sellers

Rank Fund Capital Flow
1
Jane Street
Jane Street
New York
-$5.82M
2
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$5.77M
3
Millennium Management
Millennium Management
New York
-$3.76M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$2.08M
5
Fidelity Investments
Fidelity Investments
Massachusetts
-$1.52M
Name Holding Trade Value Shares
Change 		Change in
Stake
AI
1
Alphabet Inc
California
$113M – – –
Vanguard Group
2
Vanguard Group
Pennsylvania
$37.7M +$8.02M +617,310 +19%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$37.4M -$1.52M -116,803 -3%
Sumitomo Mitsui Trust Group
4
Sumitomo Mitsui Trust Group
Japan
$34.7M +$7.42M +571,097 +19%
NAMA
5
Nikko Asset Management Americas
New York
$34.6M +$7.41M +570,232 +19%
BlackRock
6
BlackRock
New York
$31.8M +$5.78M +445,309 +15%
AIM
7
ARK Investment Management
Florida
$25M +$2.25M +173,230 +7%
T. Rowe Price Associates
8
T. Rowe Price Associates
Maryland
$20.7M -$2.08M -160,460 -7%
Fidelity International
9
Fidelity International
Bermuda
$17.2M – – –
MM
10
MWG Management
British Virgin Islands
$17.1M – – –
State Street
11
State Street
Massachusetts
$16.1M +$14M +1,080,802 +179%
RG
12
Redmile Group
California
$12.6M – – –
BBA
13
Baker Bros. Advisors
New York
$9.81M – – –
DM
14
Deerfield Management
New York
$8.45M – – –
Geode Capital Management
15
Geode Capital Management
Massachusetts
$8.08M +$3.98M +306,329 +57%
EC
16
EcoR1 Capital
California
$5.72M – – –
SB
17
Samsara BioCapital
California
$4.49M – – –
MCM
18
Moore Capital Management
New York
$4.26M – – –
GWM
19
Greenwich Wealth Management
Connecticut
$4.19M +$3M +231,021 +111%
CC
20
Casdin Capital
New York
$3.5M – – –
Northern Trust
21
Northern Trust
Illinois
$3.18M +$656K +50,527 +18%
Bank of America
22
Bank of America
North Carolina
$2.89M +$2.01M +155,127 +105%
Charles Schwab
23
Charles Schwab
California
$2.79M +$1.97M +151,426 +107%
Ensign Peak Advisors
24
Ensign Peak Advisors
Utah
$1.43M – – –
Rafferty Asset Management
25
Rafferty Asset Management
New York
$1.23M +$1.67M +128,876 New
1
2 3 4

PRME Hedge Fund Activity: Q3 2023 in Review

83 of the 6,301 institutional investors tracked by Wall St. Rank reported a position in Prime Medicine (PRME) for Q3 2023, worth a combined $472M — down 30% from $676M a quarter earlier.

Buyers outnumbered sellers: 11 funds opened new PRME positions and 6 closed out — a net gain of 5 holders — while 35 added to existing stakes and 15 trimmed.

The largest buyer was State Street, adding an estimated $14M. The largest seller was Jane Street, exiting entirely with an estimated $5.82M sold.

  • 83 institutional investors held Prime Medicine (PRME) as of Q3 2023, up from 79 in Q2 2023.
  • Funds reported $472M of Prime Medicine stock for Q3 2023, down 30% quarter-over-quarter.
  • 11 funds opened new Prime Medicine positions in Q3 2023 and 6 closed out, a net change of +5 holders.
  • The largest Prime Medicine buyer in Q3 2023 was State Street, an estimated $14M added.
  • The largest Prime Medicine seller in Q3 2023 was Jane Street, an estimated $5.82M sold.

Based on aggregated 13F filings for Q3 2023.