Goldman Sachs’s Prime Medicine PRME Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$3.38M Sell
970,425
-785,343
-45% -$2.99M ﹤0.01% 4072
2025
Q4
$6.09M Buy
1,755,768
+1,345,032
+327% +$5.98M ﹤0.01% 3561
2025
Q3
$2.28M Buy
410,736
+203,728
+98% +$828K ﹤0.01% 4360
2025
Q2
$511K Sell
207,008
-44,391
-18% -$68.4K ﹤0.01% 5146
2025
Q1
$500K Sell
251,399
-170,499
-40% -$435K ﹤0.01% 5180
2024
Q4
$1.23M Buy
421,898
+201,754
+92% +$708K ﹤0.01% 4667
2024
Q3
$852K Buy
220,144
+140,777
+177% +$652K ﹤0.01% 4747
2024
Q2
$408K Buy
79,367
+41,187
+108% +$250K ﹤0.01% 4932
2024
Q1
$267K Sell
38,180
-12,969
-25% -$98.4K ﹤0.01% 5018
2023
Q4
$453K Sell
51,149
-7,762
-13% -$59.8K ﹤0.01% 4816
2023
Q3
$562K Buy
+58,911
New +$765K ﹤0.01% 4606

Other funds holding PRME

Goldman Sachs's PRME Position: Q1 2026 in Review

Goldman Sachs reduced its Prime Medicine (PRME) stake by 45% in Q1 2026, selling an estimated $2.99M and leaving 970,425 shares worth $3.38M. The position accounts for ﹤0.01% of the portfolio, ranked #4072.

Goldman Sachs first reported a position in PRME in Q3 2023 and has held it in 11 quarters since. The position peaked at $6.09M in Q4 2025. 192 funds tracked by Wall St. Rank hold PRME as of Q1 2026.

  • Goldman Sachs held 970,425 shares of Prime Medicine worth $3.38M as of Q1 2026.
  • Goldman Sachs sold 785,343 Prime Medicine shares in Q1 2026, an estimated $2.99M.
  • Prime Medicine made up ﹤0.01% of Goldman Sachs's portfolio in Q1 2026, its #4072 holding.
  • Goldman Sachs first reported a position in Prime Medicine in Q3 2023 and has held it in 11 quarters since.
  • Goldman Sachs's Prime Medicine position peaked at $6.09M in Q4 2025.
  • 192 funds tracked by Wall St. Rank held Prime Medicine as of Q1 2026.

Based on Goldman Sachs's 13F filing for Q1 2026, filed 15 May 2026.