BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+5.18%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$11.8B
AUM Growth
+$11.8B
Cap. Flow
+$507M
Cap. Flow %
4.3%
Top 10 Hldgs %
80.71%
Holding
129
New
5
Increased
21
Reduced
21
Closed
13

Top Buys

1
ONC
BeOne Medicines Ltd. American Depositary Shares
ONC
$333M
2
SGEN
Seagen Inc. Common Stock
SGEN
$202M
3
HRTX icon
Heron Therapeutics
HRTX
$54.2M
4
AVXS
AveXis, Inc. Common Stock
AVXS
$48.5M
5
ACGN
Aceragen, Inc. Common Stock
ACGN
$37.4M

Top Sells

1
ABLX
Ablynx NV American Depositary Shares
ABLX
$108M
2
RXDX
Ignyta, Inc.
RXDX
$37M
3
IMGN
Immunogen Inc
IMGN
$16.4M
4
LGND icon
Ligand Pharmaceuticals
LGND
$10M
5
SGMO icon
Sangamo Therapeutics
SGMO
$9.61M

Sector Composition

1 Healthcare 93.86%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
INCY icon
1
Incyte
INCY
$16.5B
$2.85B 24.18% 34,230,751 +228 +0% +$19K
SGEN
2
DELISTED
Seagen Inc. Common Stock
SGEN
$2.59B 21.99% 49,575,409 +3,849,853 +8% +$202M
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$979M 8.3% 5,829,429 +1,980,198 +51% +$333M
ALXN
4
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$954M 8.08% 8,555,894 +2,030 +0% +$226K
BMRN icon
5
BioMarin Pharmaceuticals
BMRN
$11.2B
$615M 5.21% 7,583,084 – –
ACAD icon
6
Acadia Pharmaceuticals
ACAD
$4.38B
$612M 5.19% 27,228,338 – –
GHDX
7
DELISTED
Genomic Health, Inc.
GHDX
$431M 3.66% 13,789,936 +8,834 +0.1% +$276K
ASND icon
8
Ascendis Pharma
ASND
$11.8B
$186M 1.57% 2,837,352 +218,534 +8% +$14.3M
NGNE icon
9
Neurogene
NGNE
$264M
$154M 1.3% 10,934,154 – –
AVXS
10
DELISTED
AveXis, Inc. Common Stock
AVXS
$144M 1.22% 1,167,157 +392,157 +51% +$48.5M
HRTX icon
11
Heron Therapeutics
HRTX
$207M
$139M 1.18% 5,025,298 +1,964,657 +64% +$54.2M
DBVT
12
DBV Technologies
DBVT
$264M
$127M 1.08% 5,509,560 – –
ABLX
13
DELISTED
Ablynx NV American Depositary Shares
ABLX
$119M 1.01% 2,176,802 -1,984,316 -48% -$108M
SAGE
14
DELISTED
Sage Therapeutics
SAGE
$104M 0.88% 646,828 +30,314 +5% +$4.88M
ARRY
15
DELISTED
Array Biopharma Inc
ARRY
$92.3M 0.78% 5,656,196 – –
ONCE
16
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$92.2M 0.78% 1,384,130 – –
NBIX icon
17
Neurocrine Biosciences
NBIX
$13.8B
$78.3M 0.66% 944,624 -60,000 -6% -$4.98M
MRTX
18
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$78.3M 0.66% 2,549,461 – –
ARGX icon
19
argenx
ARGX
$43.6B
$77.4M 0.66% 961,754 – –
MDGL icon
20
Madrigal Pharmaceuticals
MDGL
$9.76B
$71.9M 0.61% 615,684 – –
ACGN
21
DELISTED
Aceragen, Inc. Common Stock
ACGN
$71.1M 0.6% 38,641,462 +20,325,660 +111% +$37.4M
AMRN
22
Amarin Corp
AMRN
$311M
$68.2M 0.58% 22,669,509 – –
BCRX icon
23
BioCryst Pharmaceuticals
BCRX
$1.74B
$66.8M 0.57% 14,012,172 +15,000 +0.1% +$71.6K
PHXM
24
DELISTED
PHAXIAM Therapeutics S.A.. American Depositary Shares
PHXM
$64.9M 0.55% 3,090,069 – –
CERS icon
25
Cerus
CERS
$251M
$58.9M 0.5% 10,749,937 +1,004,728 +10% +$5.51M
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