BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+22.78%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$12.2B
AUM Growth
+$12.2B
Cap. Flow
+$1.32B
Cap. Flow %
10.82%
Top 10 Hldgs %
86.71%
Holding
139
New
5
Increased
21
Reduced
9
Closed
18

Top Buys

1
INCY icon
Incyte
INCY
$1.42B
2
AVXS
AveXis, Inc. Common Stock
AVXS
$14M
3
LJPC
La Jolla Pharmaceutical Company
LJPC
$10.9M
4
ASND icon
Ascendis Pharma
ASND
$9.19M
5
NGNE icon
Neurogene
NGNE
$6.64M

Top Sells

1
ABBV icon
AbbVie
ABBV
$106M
2
DSCI
Derma Sciences, Inc. Common Stock (DE)
DSCI
$19.5M
3
ARRY
Array Biopharma Inc
ARRY
$8.94M
4
EXEL icon
Exelixis
EXEL
$8.67M
5
ARAV
Aravive, Inc. Common Stock
ARAV
$5.56M

Sector Composition

1 Healthcare 92.13%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
INCY icon
1
Incyte
INCY
$16.5B
$4.56B 37.31% 34,110,011 +10,610,924 +45% +$1.42B
SGEN
2
DELISTED
Seagen Inc. Common Stock
SGEN
$2.87B 23.51% 45,715,556 +3,700 +0% +$233K
ACAD icon
3
Acadia Pharmaceuticals
ACAD
$4.38B
$888M 7.26% 25,819,768 – –
ALXN
4
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$793M 6.49% 6,544,130 +835 +0% +$101K
GHDX
5
DELISTED
Genomic Health, Inc.
GHDX
$434M 3.55% 13,770,982 +680 +0% +$21.4K
BMRN icon
6
BioMarin Pharmaceuticals
BMRN
$11.2B
$422M 3.45% 4,806,483 – –
DBVT
7
DBV Technologies
DBVT
$264M
$194M 1.59% 5,509,560 – –
NGNE icon
8
Neurogene
NGNE
$264M
$182M 1.49% 10,934,154 +398,062 +4% +$6.64M
ONC
9
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$134M 1.1% 3,673,175 – –
AKAO
10
DELISTED
Achaogen, Inc.
AKAO
$116M 0.95% 4,582,382 – –
BCRX icon
11
BioCryst Pharmaceuticals
BCRX
$1.74B
$98.4M 0.81% 11,716,784 +752,840 +7% +$6.32M
AAAP
12
DELISTED
Advanced Accelerator Applications S.A. American Depositary Shares
AAAP
$88.6M 0.72% 2,221,706 +54,569 +3% +$2.18M
NVTA
13
DELISTED
Invitae Corporation
NVTA
$80.6M 0.66% 7,288,300 – –
AMRN
14
Amarin Corp
AMRN
$311M
$72.5M 0.59% 22,656,469 +486,960 +2% +$1.56M
ONCE
15
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$70.3M 0.58% 1,318,341 – –
ACOR
16
DELISTED
Acorda Therapeutics, Inc.
ACOR
$69.3M 0.57% 3,301,791 – –
BLCM
17
DELISTED
Bellicum Pharmaceuticals, Inc.
BLCM
$62.1M 0.51% 5,032,313 +166,666 +3% +$2.06M
CERS icon
18
Cerus
CERS
$251M
$58.1M 0.48% 13,053,275 – –
EXEL icon
19
Exelixis
EXEL
$10.1B
$56.4M 0.46% 2,603,569 -400,000 -13% -$8.67M
HRTX icon
20
Heron Therapeutics
HRTX
$207M
$41.8M 0.34% 2,783,569 +400,000 +17% +$6M
NBIX icon
21
Neurocrine Biosciences
NBIX
$13.8B
$38.8M 0.32% 895,422 – –
AVXS
22
DELISTED
AveXis, Inc. Common Stock
AVXS
$38M 0.31% 500,000 +184,700 +59% +$14M
ASND icon
23
Ascendis Pharma
ASND
$11.8B
$37.8M 0.31% 1,351,463 +328,197 +32% +$9.19M
ARAV
24
DELISTED
Aravive, Inc. Common Stock
ARAV
$35.5M 0.29% 1,660,593 -260,252 -14% -$5.56M
BLUE
25
DELISTED
bluebird bio
BLUE
$31.9M 0.26% 351,441 – –
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