BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-3.96%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$11.5B
AUM Growth
+$11.5B
Cap. Flow
+$415M
Cap. Flow %
3.6%
Top 10 Hldgs %
81.68%
Holding
129
New
8
Increased
22
Reduced
12
Closed
5

Top Buys

1
BMRN icon
BioMarin Pharmaceuticals
BMRN
$150M
2
ABLX
Ablynx NV American Depositary Shares
ABLX
$104M
3
PHXM
PHAXIAM Therapeutics S.A.. American Depositary Shares
PHXM
$68M
4
RYTM icon
Rhythm Pharmaceuticals
RYTM
$59.5M
5
ARGX icon
argenx
ARGX
$54.4M

Top Sells

1
AAAP
Advanced Accelerator Applications S.A. American Depositary Shares
AAAP
$179M
2
AKAO
Achaogen, Inc.
AKAO
$40.4M
3
NDRM
NeuroDerm Ltd. Ordinary Shares
NDRM
$22.2M
4
EXEL icon
Exelixis
EXEL
$17.5M
5
LOXO
Loxo Oncology, Inc
LOXO
$8.85M

Sector Composition

1 Healthcare 93.22%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
INCY icon
1
Incyte
INCY
$16.5B
$3.24B 28.1% 34,230,523 +200 +0% +$18.9K
SGEN
2
DELISTED
Seagen Inc. Common Stock
SGEN
$2.45B 21.2% 45,725,556 – –
ALXN
3
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$1.02B 8.87% 8,553,864 – –
ACAD icon
4
Acadia Pharmaceuticals
ACAD
$4.38B
$820M 7.11% 27,228,338 +1,408,570 +5% +$42.4M
BMRN icon
5
BioMarin Pharmaceuticals
BMRN
$11.2B
$676M 5.86% 7,583,084 +1,677,411 +28% +$150M
GHDX
6
DELISTED
Genomic Health, Inc.
GHDX
$471M 4.09% 13,781,102 +622 +0% +$21.3K
ONC
7
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$376M 3.26% 3,849,231 -49,200 -1% -$4.81M
DBVT
8
DBV Technologies
DBVT
$264M
$136M 1.17% 5,509,560 – –
NGNE icon
9
Neurogene
NGNE
$264M
$129M 1.11% 10,934,154 – –
ASND icon
10
Ascendis Pharma
ASND
$11.8B
$105M 0.91% 2,618,818 +269,978 +11% +$10.8M
ABLX
11
DELISTED
Ablynx NV American Depositary Shares
ABLX
$104M 0.9% +4,161,118 New +$104M
SAGE
12
DELISTED
Sage Therapeutics
SAGE
$102M 0.88% 616,514 +211,029 +52% +$34.8M
AMRN
13
Amarin Corp
AMRN
$311M
$90.9M 0.79% 22,669,509 – –
AVXS
14
DELISTED
AveXis, Inc. Common Stock
AVXS
$85.8M 0.74% 775,000 – –
NBIX icon
15
Neurocrine Biosciences
NBIX
$13.8B
$77.9M 0.68% 1,004,624 +387,942 +63% +$30.1M
ARRY
16
DELISTED
Array Biopharma Inc
ARRY
$72.4M 0.63% 5,656,196 +442,668 +8% +$5.67M
ONCE
17
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$71.2M 0.62% 1,384,130 – –
BCRX icon
18
BioCryst Pharmaceuticals
BCRX
$1.74B
$68.7M 0.6% 13,997,172 – –
PHXM
19
DELISTED
PHAXIAM Therapeutics S.A.. American Depositary Shares
PHXM
$68M 0.59% +3,090,069 New +$68M
NVTA
20
DELISTED
Invitae Corporation
NVTA
$66.2M 0.57% 7,288,300 – –
ARGX icon
21
argenx
ARGX
$43.6B
$60.7M 0.53% 961,754 +861,754 +862% +$54.4M
RYTM icon
22
Rhythm Pharmaceuticals
RYTM
$6.85B
$59.5M 0.52% +2,049,020 New +$59.5M
MDGL icon
23
Madrigal Pharmaceuticals
MDGL
$9.76B
$56.5M 0.49% 615,684 +557,922 +966% +$51.2M
HRTX icon
24
Heron Therapeutics
HRTX
$207M
$55.4M 0.48% 3,060,641 +272,649 +10% +$4.93M
MRTX
25
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$46.5M 0.4% 2,549,461 +280,263 +12% +$5.11M
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