BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+33.77%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$15.6B
AUM Growth
+$15.6B
Cap. Flow
+$12.7M
Cap. Flow %
0.08%
Top 10 Hldgs %
85.51%
Holding
100
New
7
Increased
16
Reduced
6
Closed
4

Top Buys

1
ASND icon
Ascendis Pharma
ASND
$65.1M
2
MYOK
MyoKardia, Inc. Common Stock
MYOK
$36.4M
3
NBIX icon
Neurocrine Biosciences
NBIX
$32.4M
4
BOLD
Audentes Therapeutics, Inc
BOLD
$31.4M
5
AXSM icon
Axsome Therapeutics
AXSM
$17.1M

Top Sells

1
GHDX
Genomic Health, Inc.
GHDX
$108M
2
ONCE
Spark Therapeutics, Inc. Common Stock
ONCE
$72M
3
ARRY
Array Biopharma Inc
ARRY
$29.2M
4
SLDB icon
Solid Biosciences
SLDB
$15.8M
5
NVAX icon
Novavax
NVAX
$8.68M

Sector Composition

1 Healthcare 93.53%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$3.74B 23.93% 51,049,760 +3,700 +0% +$271K
INCY icon
2
Incyte
INCY
$16.5B
$2.95B 18.87% 34,271,827 +20,220 +0.1% +$1.74M
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$1.58B 10.11% 11,959,824 – –
ALXN
4
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$1.16B 7.41% 8,558,068 +2,174 +0% +$294K
ACAD icon
5
Acadia Pharmaceuticals
ACAD
$4.38B
$1.07B 6.83% 39,713,842 – –
AMRN
6
Amarin Corp
AMRN
$311M
$897M 5.74% 43,210,459 +617,635 +1% +$12.8M
GHDX
7
DELISTED
Genomic Health, Inc.
GHDX
$714M 4.57% 10,198,943 -1,545,067 -13% -$108M
BMRN icon
8
BioMarin Pharmaceuticals
BMRN
$11.2B
$674M 4.32% 7,589,294 – –
ASND icon
9
Ascendis Pharma
ASND
$11.8B
$399M 2.55% 3,390,270 +552,918 +19% +$65.1M
MRTX
10
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$184M 1.18% 2,513,462 – –
MDGL icon
11
Madrigal Pharmaceuticals
MDGL
$9.76B
$146M 0.94% 1,169,278 – –
ARGX icon
12
argenx
ARGX
$43.6B
$127M 0.81% 1,019,557 – –
BCRX icon
13
BioCryst Pharmaceuticals
BCRX
$1.74B
$123M 0.79% 15,118,081 +15,000 +0.1% +$122K
HRTX icon
14
Heron Therapeutics
HRTX
$207M
$123M 0.79% 5,018,104 – –
CMTA
15
DELISTED
Clementia Pharmaceuticals Inc.
CMTA
$97.2M 0.62% 3,724,445 – –
NBIX icon
16
Neurocrine Biosciences
NBIX
$13.8B
$96.8M 0.62% 1,098,670 +368,315 +50% +$32.4M
ARRY
17
DELISTED
Array Biopharma Inc
ARRY
$93.7M 0.6% 3,842,289 -1,199,407 -24% -$29.2M
NVTA
18
DELISTED
Invitae Corporation
NVTA
$91.4M 0.59% 3,902,421 – –
ONCE
19
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$85.6M 0.55% 751,927 -632,203 -46% -$72M
CBAY
20
DELISTED
Cymabay Therapeutics
CBAY
$75.8M 0.49% 5,707,411 +789,711 +16% +$10.5M
RYTM icon
21
Rhythm Pharmaceuticals
RYTM
$6.85B
$74.2M 0.48% 2,708,200 – –
GWPH
22
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$72.2M 0.46% 428,345 – –
TCDA
23
DELISTED
Tricida, Inc. Common Stock
TCDA
$69.6M 0.45% 1,803,238 +203,238 +13% +$7.85M
CERS icon
24
Cerus
CERS
$251M
$67M 0.43% 10,749,937 – –
BOLD
25
DELISTED
Audentes Therapeutics, Inc
BOLD
$66.9M 0.43% 1,715,183 +804,720 +88% +$31.4M
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