BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+45.36%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$22.7B
AUM Growth
+$22.7B
Cap. Flow
-$175M
Cap. Flow %
-0.77%
Top 10 Hldgs %
85.22%
Holding
124
New
14
Increased
20
Reduced
17
Closed
10

Top Buys

1
MYOK
MyoKardia, Inc. Common Stock
MYOK
$134M
2
FMTX
Forma Therapeutics Holdings, Inc. Common Stock
FMTX
$93M
3
NVTA
Invitae Corporation
NVTA
$83.3M
4
ADCT icon
ADC Therapeutics
ADCT
$79M
5
ADAP
Adaptimmune Therapeutics
ADAP
$29.9M

Top Sells

1
SGEN
Seagen Inc. Common Stock
SGEN
$474M
2
RARX
Ra Pharmaceuticals, Inc. Common Stock
RARX
$101M
3
TCDA
Tricida, Inc. Common Stock
TCDA
$51.6M
4
NBIX icon
Neurocrine Biosciences
NBIX
$40.7M
5
GWPH
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$22.8M

Sector Composition

1 Healthcare 97.75%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$8.03B 35.43% 47,269,424 -2,790,816 -6% -$474M
INCY icon
2
Incyte
INCY
$16.5B
$3.33B 14.67% 31,999,081 +20,296 +0.1% +$2.11M
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$2.22B 9.79% 11,777,285 – –
ACAD icon
4
Acadia Pharmaceuticals
ACAD
$4.38B
$2.03B 8.96% 41,904,586 – –
ALXN
5
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$983M 4.34% 8,760,794 – –
BMRN icon
6
BioMarin Pharmaceuticals
BMRN
$11.2B
$936M 4.13% 7,589,294 – –
KOD icon
7
Kodiak Sciences
KOD
$478M
$626M 2.76% 11,574,538 – –
ASND icon
8
Ascendis Pharma
ASND
$11.8B
$501M 2.21% 3,390,270 – –
NVTA
9
DELISTED
Invitae Corporation
NVTA
$359M 1.58% 11,850,962 +2,750,347 +30% +$83.3M
MYOK
10
DELISTED
MyoKardia, Inc. Common Stock
MYOK
$306M 1.35% 3,164,234 +1,390,000 +78% +$134M
AMRN
11
Amarin Corp
AMRN
$311M
$239M 1.05% 34,496,685 – –
ARGX icon
12
argenx
ARGX
$43.6B
$230M 1.01% 1,019,557 – –
IGMS
13
DELISTED
IGM Biosciences
IGMS
$230M 1.01% 3,144,223 +223 +0% +$16.3K
MDGL icon
14
Madrigal Pharmaceuticals
MDGL
$9.76B
$170M 0.75% 1,499,212 – –
MRTX
15
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$161M 0.71% 1,409,784 – –
EXAS icon
16
Exact Sciences
EXAS
$8.98B
$161M 0.71% 1,846,139 – –
NBIX icon
17
Neurocrine Biosciences
NBIX
$13.8B
$111M 0.49% 906,986 -333,257 -27% -$40.7M
PRNB
18
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$94.5M 0.42% 1,580,873 -374,540 -19% -$22.4M
FMTX
19
DELISTED
Forma Therapeutics Holdings, Inc. Common Stock
FMTX
$93M 0.41% +2,000,000 New +$93M
CERS icon
20
Cerus
CERS
$251M
$90.5M 0.4% 13,713,195 – –
HRTX icon
21
Heron Therapeutics
HRTX
$207M
$88.5M 0.39% 6,018,104 – –
INSM icon
22
Insmed
INSM
$28.8B
$83.3M 0.37% 3,025,384 – –
AXSM icon
23
Axsome Therapeutics
AXSM
$6.05B
$83.1M 0.37% 1,009,757 +120,000 +13% +$9.87M
ADCT icon
24
ADC Therapeutics
ADCT
$345M
$79M 0.35% +1,687,500 New +$79M
BCEL
25
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$75.2M 0.33% 3,532,760 – –
1
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