BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-1.89%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$14.7B
AUM Growth
+$14.7B
Cap. Flow
-$316M
Cap. Flow %
-2.15%
Top 10 Hldgs %
84.38%
Holding
107
New
11
Increased
15
Reduced
16
Closed
4

Top Buys

1
BCEL
Atreca, Inc. Class A Common Stock
BCEL
$66.6M
2
ADPT icon
Adaptive Biotechnologies
ADPT
$56.3M
3
RARX
Ra Pharmaceuticals, Inc. Common Stock
RARX
$29.4M
4
NBIX icon
Neurocrine Biosciences
NBIX
$26.7M
5
HRTX icon
Heron Therapeutics
HRTX
$18.6M

Top Sells

1
INCY icon
Incyte
INCY
$195M
2
CMTA
Clementia Pharmaceuticals Inc.
CMTA
$97.2M
3
SGEN
Seagen Inc. Common Stock
SGEN
$68.7M
4
GHDX
Genomic Health, Inc.
GHDX
$54.6M
5
ARRY
Array Biopharma Inc
ARRY
$46M

Sector Composition

1 Healthcare 94.64%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$3.46B 23.55% 50,057,277 -992,483 -2% -$68.7M
INCY icon
2
Incyte
INCY
$16.5B
$2.72B 18.46% 31,976,193 -2,295,634 -7% -$195M
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$1.46B 9.92% 11,777,285 -182,539 -2% -$22.6M
ALXN
4
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$1.08B 7.35% 8,258,068 -300,000 -4% -$39.3M
ACAD icon
5
Acadia Pharmaceuticals
ACAD
$4.38B
$1.05B 7.14% 39,292,086 -421,756 -1% -$11.3M
AMRN
6
Amarin Corp
AMRN
$311M
$806M 5.47% 41,544,288 -1,666,171 -4% -$32.3M
BMRN icon
7
BioMarin Pharmaceuticals
BMRN
$11.2B
$650M 4.42% 7,589,294 – –
GHDX
8
DELISTED
Genomic Health, Inc.
GHDX
$539M 3.66% 9,260,922 -938,021 -9% -$54.6M
ASND icon
9
Ascendis Pharma
ASND
$11.8B
$390M 2.65% 3,390,270 – –
MRTX
10
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$259M 1.76% 2,513,462 – –
ARGX icon
11
argenx
ARGX
$43.6B
$144M 0.98% 1,019,557 – –
ARRY
12
DELISTED
Array Biopharma Inc
ARRY
$132M 0.9% 2,848,567 -993,722 -26% -$46M
MDGL icon
13
Madrigal Pharmaceuticals
MDGL
$9.76B
$123M 0.83% 1,169,278 – –
NBIX icon
14
Neurocrine Biosciences
NBIX
$13.8B
$119M 0.81% 1,415,283 +316,613 +29% +$26.7M
HRTX icon
15
Heron Therapeutics
HRTX
$207M
$112M 0.76% 6,018,104 +1,000,000 +20% +$18.6M
KOD icon
16
Kodiak Sciences
KOD
$478M
$107M 0.73% 9,145,115 – –
NVTA
17
DELISTED
Invitae Corporation
NVTA
$91.7M 0.62% 3,902,421 – –
TCDA
18
DELISTED
Tricida, Inc. Common Stock
TCDA
$77.7M 0.53% 1,969,905 +166,667 +9% +$6.58M
ONCE
19
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$77M 0.52% 751,927 – –
BCEL
20
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$66.6M 0.45% +3,532,760 New +$66.6M
GWPH
21
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$63.9M 0.43% 370,845 -57,500 -13% -$9.91M
INSM icon
22
Insmed
INSM
$28.8B
$63M 0.43% 2,462,216 +384,615 +19% +$9.85M
CERS icon
23
Cerus
CERS
$251M
$60.4M 0.41% 10,749,937 – –
RYTM icon
24
Rhythm Pharmaceuticals
RYTM
$6.85B
$59.6M 0.4% 2,708,200 – –
PRNB
25
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$59.3M 0.4% 1,787,807 – –
1
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