BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-1.31%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$15.3B
AUM Growth
+$15.3B
Cap. Flow
-$285M
Cap. Flow %
-1.86%
Top 10 Hldgs %
84.69%
Holding
129
New
12
Increased
7
Reduced
17
Closed
13

Top Buys

1
AKRO icon
Akero Therapeutics
AKRO
$76.6M
2
RYTM icon
Rhythm Pharmaceuticals
RYTM
$47.5M
3
CINC
CinCor Pharma, Inc. Common Stock
CINC
$26.5M
4
IDYA icon
IDEAYA Biosciences
IDYA
$24.9M
5
BCYC
Bicycle Therapeutics
BCYC
$19.6M

Top Sells

1
ARGX icon
argenx
ARGX
$296M
2
LEGN icon
Legend Biotech
LEGN
$47.1M
3
INSM icon
Insmed
INSM
$46M
4
KRYS icon
Krystal Biotech
KRYS
$26.9M
5
PACB icon
Pacific Biosciences
PACB
$25.1M

Sector Composition

1 Healthcare 98.97%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$6.42B 42.04% 46,912,266 – –
INCY icon
2
Incyte
INCY
$16.5B
$2.41B 15.78% 36,154,574 +457 +0% +$30.5K
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$1.57B 10.3% 11,668,897 – –
ACAD icon
4
Acadia Pharmaceuticals
ACAD
$4.38B
$686M 4.49% 41,923,486 – –
BMRN icon
5
BioMarin Pharmaceuticals
BMRN
$11.2B
$646M 4.23% 7,620,494 – –
ASND icon
6
Ascendis Pharma
ASND
$11.8B
$501M 3.28% 4,852,655 – –
GBT
7
DELISTED
Global Blood Therapeutics, Inc.
GBT
$254M 1.66% 3,732,502 – –
BCRX icon
8
BioCryst Pharmaceuticals
BCRX
$1.74B
$160M 1.05% 12,710,818 – –
RYTM icon
9
Rhythm Pharmaceuticals
RYTM
$6.85B
$149M 0.97% 6,062,702 +1,937,640 +47% +$47.5M
KOD icon
10
Kodiak Sciences
KOD
$478M
$134M 0.88% 17,310,490 – –
IMCR icon
11
Immunocore
IMCR
$1.62B
$118M 0.77% 2,520,731 +1 +0% +$47
ABCL icon
12
AbCellera Biologics
ABCL
$1.25B
$103M 0.68% 10,450,180 – –
ARGX icon
13
argenx
ARGX
$43.6B
$98.9M 0.65% 280,159 -839,398 -75% -$296M
MRTX
14
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$98.5M 0.64% 1,409,784 – –
MDGL icon
15
Madrigal Pharmaceuticals
MDGL
$9.76B
$97.4M 0.64% 1,499,213 – –
CCXI
16
DELISTED
ChemoCentryx, Inc.
CCXI
$92.6M 0.61% 1,792,657 – –
TVTX icon
17
Travere Therapeutics
TVTX
$1.56B
$81.3M 0.53% 3,300,009 – –
AKRO icon
18
Akero Therapeutics
AKRO
$3.74B
$80.6M 0.53% 2,368,378 +2,250,000 +1,901% +$76.6M
TRDA icon
19
Entrada Therapeutics
TRDA
$208M
$76.7M 0.5% 4,865,819 – –
IGMS
20
DELISTED
IGM Biosciences
IGMS
$71.8M 0.47% 3,156,102 – –
REPL icon
21
Replimune Group
REPL
$422M
$67.2M 0.44% 3,893,843 +302,762 +8% +$5.23M
PRLD icon
22
Prelude Therapeutics
PRLD
$68.5M
$66.9M 0.44% 10,123,824 – –
KYMR icon
23
Kymera Therapeutics
KYMR
$2.95B
$62.7M 0.41% 2,879,825 – –
HZNP
24
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$60M 0.39% 969,727 -178,777 -16% -$11.1M
CERS icon
25
Cerus
CERS
$251M
$57.8M 0.38% 16,067,558 – –
1
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