BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+3.62%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$22.8B
AUM Growth
+$22.8B
Cap. Flow
-$610M
Cap. Flow %
-2.68%
Top 10 Hldgs %
81.57%
Holding
135
New
6
Increased
16
Reduced
10
Closed
15

Top Buys

1
VERV
Verve Therapeutics
VERV
$85.3M
2
LEGN icon
Legend Biotech
LEGN
$63.6M
3
APLS icon
Apellis Pharmaceuticals
APLS
$37.8M
4
HRTX icon
Heron Therapeutics
HRTX
$33.2M
5
JBIO
Jade Biosciences, Inc. Common Stock
JBIO
$32.6M

Top Sells

1
ALXN
Alexion Pharmaceuticals Inc
ALXN
$611M
2
NVTA
Invitae Corporation
NVTA
$186M
3
PTGX icon
Protagonist Therapeutics
PTGX
$44M
4
CCXI
ChemoCentryx, Inc.
CCXI
$33.7M
5
ALT icon
Altimmune
ALT
$16.6M

Sector Composition

1 Healthcare 97.75%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$7.47B 32.79% 47,288,259 +17,500 +0% +$2.76M
ONC
2
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$4B 17.59% 11,668,897 – –
INCY icon
3
Incyte
INCY
$16.5B
$2.69B 11.83% 32,021,732 +20,345 +0.1% +$1.71M
KOD icon
4
Kodiak Sciences
KOD
$478M
$1.31B 5.77% 14,137,881 +257,929 +2% +$24M
ACAD icon
5
Acadia Pharmaceuticals
ACAD
$4.38B
$1.02B 4.49% 41,910,704 – –
BMRN icon
6
BioMarin Pharmaceuticals
BMRN
$11.2B
$633M 2.78% 7,589,294 – –
ASND icon
7
Ascendis Pharma
ASND
$11.8B
$466M 2.05% 3,540,270 – –
NVTA
8
DELISTED
Invitae Corporation
NVTA
$346M 1.52% 10,248,575 -5,500,607 -35% -$186M
ARGX icon
9
argenx
ARGX
$43.6B
$337M 1.48% 1,119,557 – –
PRLD icon
10
Prelude Therapeutics
PRLD
$68.5M
$290M 1.27% 10,123,824 – –
IGMS
11
DELISTED
IGM Biosciences
IGMS
$263M 1.15% 3,156,102 – –
ABCL icon
12
AbCellera Biologics
ABCL
$1.25B
$230M 1.01% 10,450,180 – –
MRTX
13
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$228M 1% 1,409,784 – –
BCRX icon
14
BioCryst Pharmaceuticals
BCRX
$1.74B
$201M 0.88% 12,710,818 – –
MDGL icon
15
Madrigal Pharmaceuticals
MDGL
$9.76B
$146M 0.64% 1,499,213 – –
APLS icon
16
Apellis Pharmaceuticals
APLS
$3.48B
$144M 0.63% 2,271,917 +597,913 +36% +$37.8M
HRTX icon
17
Heron Therapeutics
HRTX
$207M
$126M 0.55% 8,131,678 +2,136,974 +36% +$33.2M
AMRN
18
Amarin Corp
AMRN
$311M
$116M 0.51% 26,453,422 – –
GBT
19
DELISTED
Global Blood Therapeutics, Inc.
GBT
$113M 0.49% 3,217,441 – –
PACB icon
20
Pacific Biosciences
PACB
$393M
$112M 0.49% 3,201,972 – –
IMCR icon
21
Immunocore
IMCR
$1.62B
$98.4M 0.43% 2,520,730 – –
KYMR icon
22
Kymera Therapeutics
KYMR
$2.95B
$95M 0.42% 1,959,211 – –
VSTM icon
23
Verastem
VSTM
$569M
$87.5M 0.38% 21,491,630 +4,472,336 +26% +$18.2M
VERV
24
DELISTED
Verve Therapeutics
VERV
$85.3M 0.37% +1,416,530 New +$85.3M
TLIS
25
DELISTED
Talis Biomedical Corporation Common Stock
TLIS
$83.6M 0.37% 7,574,835 – –
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