BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+12.1%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$12.3B
AUM Growth
+$12.3B
Cap. Flow
+$170M
Cap. Flow %
1.38%
Top 10 Hldgs %
85.9%
Holding
130
New
9
Increased
24
Reduced
9
Closed
9

Top Buys

1
ARRY
Array Biopharma Inc
ARRY
$44.6M
2
ONC
BeOne Medicines Ltd. American Depositary Shares
ONC
$23.3M
3
ASND icon
Ascendis Pharma
ASND
$21.7M
4
AVXS
AveXis, Inc. Common Stock
AVXS
$14.5M
5
CBAY
Cymabay Therapeutics
CBAY
$13.7M

Top Sells

1
SGMO icon
Sangamo Therapeutics
SGMO
$30M
2
AKAO
Achaogen, Inc.
AKAO
$14.6M
3
LJPC
La Jolla Pharmaceutical Company
LJPC
$12.2M
4
BLUE
bluebird bio
BLUE
$8.24M
5
LOXO
Loxo Oncology, Inc
LOXO
$3.89M

Sector Composition

1 Healthcare 93.02%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
INCY icon
1
Incyte
INCY
$16.5B
$4B 32.41% 34,230,323 +100,162 +0.3% +$11.7M
SGEN
2
DELISTED
Seagen Inc. Common Stock
SGEN
$2.49B 20.18% 45,725,556 – –
ALXN
3
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$1.2B 9.73% 8,553,864 – –
ACAD icon
4
Acadia Pharmaceuticals
ACAD
$4.38B
$973M 7.89% 25,819,768 – –
BMRN icon
5
BioMarin Pharmaceuticals
BMRN
$11.2B
$550M 4.46% 5,905,673 – –
GHDX
6
DELISTED
Genomic Health, Inc.
GHDX
$442M 3.59% 13,780,480 +614 +0% +$19.7K
ONC
7
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$403M 3.27% 3,898,431 +225,256 +6% +$23.3M
DBVT
8
DBV Technologies
DBVT
$264M
$234M 1.9% 5,509,560 – –
NGNE icon
9
Neurogene
NGNE
$264M
$155M 1.26% 10,934,154 – –
AAAP
10
DELISTED
Advanced Accelerator Applications S.A. American Depositary Shares
AAAP
$152M 1.23% 2,243,262 +21,556 +1% +$1.46M
ONCE
11
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$123M 1% 1,384,130 +65,789 +5% +$5.87M
ASND icon
12
Ascendis Pharma
ASND
$11.8B
$85.1M 0.69% 2,348,840 +597,377 +34% +$21.7M
AMRN
13
Amarin Corp
AMRN
$311M
$79.3M 0.64% 22,669,509 – –
AVXS
14
DELISTED
AveXis, Inc. Common Stock
AVXS
$75M 0.61% 775,000 +150,000 +24% +$14.5M
BCRX icon
15
BioCryst Pharmaceuticals
BCRX
$1.74B
$73.3M 0.59% 13,997,172 +2,280,388 +19% +$11.9M
NVTA
16
DELISTED
Invitae Corporation
NVTA
$68.3M 0.55% 7,288,300 – –
ARRY
17
DELISTED
Array Biopharma Inc
ARRY
$64.1M 0.52% 5,213,528 +3,627,615 +229% +$44.6M
AKAO
18
DELISTED
Achaogen, Inc.
AKAO
$62M 0.5% 3,886,878 -917,726 -19% -$14.6M
BLCM
19
DELISTED
Bellicum Pharmaceuticals, Inc.
BLCM
$58.1M 0.47% 5,032,313 – –
EXEL icon
20
Exelixis
EXEL
$10.1B
$50.4M 0.41% 2,082,012 – –
HRTX icon
21
Heron Therapeutics
HRTX
$207M
$45M 0.37% 2,787,992 +4,423 +0.2% +$71.4K
NBIX icon
22
Neurocrine Biosciences
NBIX
$13.8B
$37.8M 0.31% 616,682 – –
BLUE
23
DELISTED
bluebird bio
BLUE
$33.2M 0.27% 241,441 -60,000 -20% -$8.24M
SGMO icon
24
Sangamo Therapeutics
SGMO
$157M
$31.7M 0.26% 2,113,376 -2,000,000 -49% -$30M
ABEO icon
25
Abeona Therapeutics
ABEO
$350M
$28.7M 0.23% 1,684,364 – –
1
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