BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-9.09%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$17.4B
AUM Growth
+$17.4B
Cap. Flow
+$303M
Cap. Flow %
1.74%
Top 10 Hldgs %
85.01%
Holding
123
New
2
Increased
15
Reduced
4
Closed
3

Top Buys

1
INCY icon
Incyte
INCY
$201M
2
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$31.5M
3
TSVT
2seventy bio
TSVT
$21M
4
REPL icon
Replimune Group
REPL
$17.3M
5
TVTX icon
Travere Therapeutics
TVTX
$16.3M

Top Sells

1
CCXI
ChemoCentryx, Inc.
CCXI
$17.9M
2
LEGN icon
Legend Biotech
LEGN
$17.4M
3
OPT
Opthea Limited American Depositary Shares
OPT
$3.43M
4
ALBO
Albireo Pharma, Inc. Common Stock
ALBO
$2.43M
5
GMDA
Gamida Cell Ltd. Ordinary Shares
GMDA
$1.55M

Sector Composition

1 Healthcare 98.92%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$6.76B 38.83% 46,912,266 +18,902 +0% +$2.72M
INCY icon
2
Incyte
INCY
$16.5B
$2.87B 16.5% 36,153,684 +2,535,621 +8% +$201M
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$2.2B 12.65% 11,668,897 – –
ACAD icon
4
Acadia Pharmaceuticals
ACAD
$4.38B
$1.02B 5.83% 41,910,704 – –
BMRN icon
5
BioMarin Pharmaceuticals
BMRN
$11.2B
$588M 3.38% 7,620,494 – –
ASND icon
6
Ascendis Pharma
ASND
$11.8B
$533M 3.06% 4,541,604 – –
ARGX icon
7
argenx
ARGX
$43.6B
$353M 2.03% 1,119,557 – –
BCRX icon
8
BioCryst Pharmaceuticals
BCRX
$1.74B
$207M 1.19% 12,710,818 – –
MDGL icon
9
Madrigal Pharmaceuticals
MDGL
$9.76B
$147M 0.85% 1,499,213 – –
KOD icon
10
Kodiak Sciences
KOD
$478M
$123M 0.71% 15,931,045 +1,249,741 +9% +$9.65M
MRTX
11
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$116M 0.67% 1,409,784 – –
GBT
12
DELISTED
Global Blood Therapeutics, Inc.
GBT
$115M 0.66% 3,314,765 – –
ABCL icon
13
AbCellera Biologics
ABCL
$1.25B
$102M 0.59% 10,450,180 – –
KYMR icon
14
Kymera Therapeutics
KYMR
$2.95B
$101M 0.58% 2,384,742 – –
HZNP
15
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$94.6M 0.54% 898,842 +299,732 +50% +$31.5M
TVTX icon
16
Travere Therapeutics
TVTX
$1.56B
$85M 0.49% 3,300,009 +630,955 +24% +$16.3M
IGMS
17
DELISTED
IGM Biosciences
IGMS
$84.4M 0.48% 3,156,102 – –
NVTA
18
DELISTED
Invitae Corporation
NVTA
$78.7M 0.45% 9,873,488 – –
IMCR icon
19
Immunocore
IMCR
$1.62B
$75.4M 0.43% 2,520,730 – –
CERS icon
20
Cerus
CERS
$251M
$75.3M 0.43% 13,713,195 – –
LEGN icon
21
Legend Biotech
LEGN
$6.41B
$73M 0.42% 2,008,999 -480,004 -19% -$17.4M
PRLD icon
22
Prelude Therapeutics
PRLD
$68.5M
$69.9M 0.4% 10,123,824 – –
AMRN
23
Amarin Corp
AMRN
$311M
$69.6M 0.4% 21,169,805 – –
NBIX icon
24
Neurocrine Biosciences
NBIX
$13.8B
$63.5M 0.36% 676,975 – –
MRUS icon
25
Merus
MRUS
$4.98B
$53.9M 0.31% 2,037,469 – –
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