BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-18.21%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$12.2B
AUM Growth
+$12.2B
Cap. Flow
-$49.6M
Cap. Flow %
-0.41%
Top 10 Hldgs %
86.1%
Holding
101
New
4
Increased
12
Reduced
21
Closed
10

Top Buys

1
ACAD icon
Acadia Pharmaceuticals
ACAD
$182M
2
AMRN
Amarin Corp
AMRN
$116M
3
KOD icon
Kodiak Sciences
KOD
$64.9M
4
CMTA
Clementia Pharmaceuticals Inc.
CMTA
$21.1M
5
KRYS icon
Krystal Biotech
KRYS
$13.9M

Top Sells

1
GHDX
Genomic Health, Inc.
GHDX
$132M
2
SAGE
Sage Therapeutics
SAGE
$80.2M
3
NVTA
Invitae Corporation
NVTA
$49.7M
4
ECYT
Endocyte, Inc. Common Stock
ECYT
$45.3M
5
GLPG icon
Galapagos
GLPG
$19.5M

Sector Composition

1 Healthcare 92.2%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$2.89B 23.68% 51,046,060 – –
INCY icon
2
Incyte
INCY
$16.5B
$2.18B 17.83% 34,251,607 +298 +0% +$19K
ONC
3
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$1.68B 13.74% 11,959,824 – –
ALXN
4
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$833M 6.82% 8,555,894 – –
GHDX
5
DELISTED
Genomic Health, Inc.
GHDX
$756M 6.19% 11,744,010 -2,046,960 -15% -$132M
BMRN icon
6
BioMarin Pharmaceuticals
BMRN
$11.2B
$646M 5.29% 7,589,294 +6,210 +0.1% +$529K
ACAD icon
7
Acadia Pharmaceuticals
ACAD
$4.38B
$642M 5.26% 39,713,842 +11,274,728 +40% +$182M
AMRN
8
Amarin Corp
AMRN
$311M
$580M 4.75% 42,592,824 +8,523,315 +25% +$116M
ASND icon
9
Ascendis Pharma
ASND
$11.8B
$178M 1.46% 2,837,352 – –
MDGL icon
10
Madrigal Pharmaceuticals
MDGL
$9.76B
$132M 1.08% 1,169,278 – –
HRTX icon
11
Heron Therapeutics
HRTX
$207M
$130M 1.07% 5,018,104 -7,194 -0.1% -$187K
BCRX icon
12
BioCryst Pharmaceuticals
BCRX
$1.74B
$122M 1% 15,103,081 – –
MRTX
13
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$107M 0.87% 2,513,462 – –
ARGX icon
14
argenx
ARGX
$43.6B
$97.9M 0.8% 1,019,557 – –
KNSA icon
15
Kiniksa Pharmaceuticals
KNSA
$2.48B
$84.3M 0.69% 3,000,000 – –
RYTM icon
16
Rhythm Pharmaceuticals
RYTM
$6.85B
$72.8M 0.6% 2,708,200 – –
ARRY
17
DELISTED
Array Biopharma Inc
ARRY
$71.8M 0.59% 5,041,696 -614,500 -11% -$8.76M
KOD icon
18
Kodiak Sciences
KOD
$478M
$64.9M 0.53% +9,145,115 New +$64.9M
CERS icon
19
Cerus
CERS
$251M
$54.5M 0.45% 10,749,937 – –
ONCE
20
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$54.2M 0.44% 1,384,130 – –
NBIX icon
21
Neurocrine Biosciences
NBIX
$13.8B
$52.2M 0.43% 730,355 -214,269 -23% -$15.3M
PRNB
22
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$49M 0.4% 1,787,807 – –
CMTA
23
DELISTED
Clementia Pharmaceuticals Inc.
CMTA
$43.8M 0.36% 3,724,445 +1,790,821 +93% +$21.1M
NVTA
24
DELISTED
Invitae Corporation
NVTA
$43.2M 0.35% 3,902,421 -4,496,990 -54% -$49.7M
GWPH
25
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$41.7M 0.34% 428,345 +31,645 +8% +$3.08M
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