BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+4.11%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$14.7B
AUM Growth
+$14.7B
Cap. Flow
+$64.6M
Cap. Flow %
0.44%
Top 10 Hldgs %
85.95%
Holding
111
New
8
Increased
15
Reduced
6
Closed
2

Top Buys

1
NVTA
Invitae Corporation
NVTA
$94.2M
2
ACAD icon
Acadia Pharmaceuticals
ACAD
$56.2M
3
IGMS
IGM Biosciences
IGMS
$55.8M
4
ALLK
Allakos
ALLK
$26.7M
5
MYOK
MyoKardia, Inc. Common Stock
MYOK
$26.1M

Top Sells

1
ARRY
Array Biopharma Inc
ARRY
$132M
2
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$94M
3
CPRX icon
Catalyst Pharmaceutical
CPRX
$6.46M
4
BCRX icon
BioCryst Pharmaceuticals
BCRX
$4.75M
5
INSM icon
Insmed
INSM
$4.1M

Sector Composition

1 Healthcare 93.55%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$4.27B 29.08% 50,057,277 – –
INCY icon
2
Incyte
INCY
$16.5B
$2.37B 16.15% 31,976,557 +364 +0% +$27K
ACAD icon
3
Acadia Pharmaceuticals
ACAD
$4.38B
$1.47B 10% 40,854,586 +1,562,500 +4% +$56.2M
ONC
4
BeOne Medicines Ltd. American Depositary Shares
ONC
$36.4B
$1.44B 9.81% 11,777,285 – –
ALXN
5
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$809M 5.5% 8,258,068 – –
AMRN
6
Amarin Corp
AMRN
$311M
$630M 4.28% 41,544,288 – –
GHDX
7
DELISTED
Genomic Health, Inc.
GHDX
$627M 4.27% 9,244,665 -16,257 -0.2% -$1.1M
BMRN icon
8
BioMarin Pharmaceuticals
BMRN
$11.2B
$512M 3.48% 7,589,294 – –
ASND icon
9
Ascendis Pharma
ASND
$11.8B
$327M 2.22% 3,390,270 – –
NVTA
10
DELISTED
Invitae Corporation
NVTA
$169M 1.15% 8,792,678 +4,890,257 +125% +$94.2M
KOD icon
11
Kodiak Sciences
KOD
$478M
$132M 0.89% 9,145,116 +1 +0% +$14
NBIX icon
12
Neurocrine Biosciences
NBIX
$13.8B
$128M 0.87% 1,415,283 – –
ARGX icon
13
argenx
ARGX
$43.6B
$116M 0.79% 1,019,557 – –
HRTX icon
14
Heron Therapeutics
HRTX
$207M
$111M 0.76% 6,018,104 – –
MRTX
15
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$102M 0.69% 1,307,220 -1,206,242 -48% -$94M
MDGL icon
16
Madrigal Pharmaceuticals
MDGL
$9.76B
$101M 0.69% 1,169,278 – –
MYOK
17
DELISTED
MyoKardia, Inc. Common Stock
MYOK
$79.1M 0.54% 1,517,237 +500,931 +49% +$26.1M
ONCE
18
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$72.9M 0.5% 751,927 – –
TCDA
19
DELISTED
Tricida, Inc. Common Stock
TCDA
$60.8M 0.41% 1,969,905 – –
RYTM icon
20
Rhythm Pharmaceuticals
RYTM
$6.85B
$58.5M 0.4% 2,708,200 – –
IGMS
21
DELISTED
IGM Biosciences
IGMS
$55.8M 0.38% +3,144,000 New +$55.8M
RARX
22
DELISTED
Ra Pharmaceuticals, Inc. Common Stock
RARX
$55.5M 0.38% 2,345,496 +543,801 +30% +$12.9M
CERS icon
23
Cerus
CERS
$251M
$55.4M 0.38% 10,749,937 – –
DBVT
24
DBV Technologies
DBVT
$264M
$47.4M 0.32% 5,509,560 – –
PRNB
25
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$46.7M 0.32% 1,654,029 -133,778 -7% -$3.78M
1
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