Baker Bros. Advisors’s Syros Pharmaceuticals, Inc. Common Stock SYRS Stock Holding History

Quarter	Market Value	Status	Shares	Shares Change %	Trade Value	Portfolio Weight	Portfolio Position
2021 Q3	–	Sell	-65,497	Closed	-$357K	–	129
2021 Q2	$357K	Sell	65,497 -624,670	-91%	-$3.4M	﹤0.01%	120
2021 Q1	$5.16M	Hold	690,167	–	–	0.02%	92
2020 Q4	$7.49M	Hold	690,167	–	–	0.03%	82
2020 Q3	$6.1M	Hold	690,167	–	–	0.02%	76
2020 Q2	$7.36M	Hold	690,167	–	–	0.03%	72
2020 Q1	$4.09M	Hold	690,167	–	–	0.03%	72
2019 Q4	$4.77M	Sell	690,167 -284,668	-29%	-$1.97M	0.03%	70
2019 Q3	$10.1M	Hold	974,835	–	–	0.07%	51
2019 Q2	$9.03M	Buy	974,835 +400,000	+70%	+$3.7M	0.06%	53
2019 Q1	$5.25M	Hold	574,835	–	–	0.03%	59
2018 Q4	$3.2M	Hold	574,835	–	–	0.03%	64
2018 Q3	$6.85M	Hold	574,835	–	–	0.05%	63
2018 Q2	$5.87M	Hold	574,835	–	–	0.04%	68
2018 Q1	$7.46M	Hold	574,835	–	–	0.06%	67
2017 Q4	$5.59M	Hold	574,835	–	–	0.05%	75
2017 Q3	$8.46M	Hold	574,835	–	–	0.07%	57
2017 Q2	$9.25M	Buy	574,835 +370,370	+181%	+$5.96M	0.08%	49
2017 Q1	$3.26M	Hold	204,465	–	–	0.03%	75
2016 Q4	$2.49M	Hold	204,465	–	–	0.02%	86
2016 Q3	$2.84M	Hold	204,465	–	–	0.03%	81
2016 Q2	$3.71M	Buy	+204,465	New	+$3.71M	0.04%	76