SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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45 hedge funds and large institutions have $205M invested in Syros Pharmaceuticals, Inc. Common Stock in 2017 Q1 according to their latest regulatory filings, with 8 funds opening new positions, 15 increasing their positions, 8 reducing their positions, and 1 closing their positions.

Holders
45
Holders Change
+3
Holders Change %
+7.14%
% of All Funds
1.12%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
8
Increased
15
Reduced
8
Closed
1
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
BlackRock
1
BlackRock
New York
$2.86M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$2.1M
3
OM
3
Opaleye Management
Massachusetts
$400K
4
State Street
4
State Street
Massachusetts
$976K
5
Wells Fargo
5
Wells Fargo
California
$225K

Top Sellers

1
DM
1
Deerfield Management
New York
$25.7M
2
Morgan Stanley
2
Morgan Stanley
New York
$173K
3
Goldman Sachs
3
Goldman Sachs
New York
$0
4
WMSA
4
Weiss Multi-Strategy Advisers
New York
$637K
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$1.92M
Name Market Value Shares Shares
Change 		Shares
Change %
FP
1
Flagship Pioneering
Massachusetts
$76.6M 4,806,656 – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
$55.9M 3,508,937 +1,867 +0.1%
DM
3
Deerfield Management
New York
$25.7M 1,615,136 -197,642 -11%
RG
4
Redmile Group
California
$15.2M 952,740 +4,300 +0.5%
AC
5
Aisling Capital
New York
$8.1M 508,565 – –
BBA
6
Baker Bros. Advisors
New York
$3.26M 204,465 – –
CC
7
Casdin Capital
New York
$2.9M 182,141 – –
BlackRock
8
BlackRock
New York
$2.86M 179,368 +179,122 +72,814%
EAM
9
Eventide Asset Management
Massachusetts
$2.39M 150,000 – –
Vanguard Group
10
Vanguard Group
Pennsylvania
$2.1M 132,096 +96,729 +274%
JPMorgan Chase & Co
11
JPMorgan Chase & Co
New York
$1.92M 120,556 -8,562 -7%
Alyeska Investment Group
12
Alyeska Investment Group
Illinois
$1.81M 113,826 +283 +0.2%
EC
13
EcoR1 Capital
California
$1.01M 63,596 – –
State Street
14
State Street
Massachusetts
$976K 61,247 +15,800 +35%
AIC
15
AWM Investment Company
New York
$757K 47,550 – –
Geode Capital Management
16
Geode Capital Management
Massachusetts
$638K 40,058 +4,222 +12%
WMSA
17
Weiss Multi-Strategy Advisers
New York
$637K 40,000 -9,000 -18%
Northern Trust
18
Northern Trust
Illinois
$527K 33,098 +6,050 +22%
OM
19
Opaleye Management
Massachusetts
$400K 25,149 +25,149 New
Wells Fargo
20
Wells Fargo
California
$225K 14,100 +14,100 New
Millennium Management
21
Millennium Management
New York
$186K 11,646 +11,646 New
Bank of New York Mellon
22
Bank of New York Mellon
New York
$185K 11,642 +11,642 New
Morgan Stanley
23
Morgan Stanley
New York
$173K 10,832 -20,212 -65%
California State Teachers Retirement System (CalSTRS)
24
California State Teachers Retirement System (CalSTRS)
California
$153K 9,600 – –
GT
25
Glenmede Trust
Pennsylvania
$148K 9,324 – –
1
2