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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

94 hedge funds and large institutions have $53.1M invested in Syros Pharmaceuticals, Inc. Common Stock in 2022 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 26 increasing their positions, 31 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

136% more call options, than puts

Call options by funds: $33K | Put options by funds: $14K

36% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 11

4% more funds holding

Funds holding: 9094 (+4)

16% less repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 31

68% less capital invested

Capital invested by funds: $166M → $53.1M (-$113M)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
94
Holders Change
+4
Holders Change %
+4.44%
% of All Funds
1.48%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
15
Increased
26
Reduced
31
Closed
11
Calls
$33K
Puts
$14K
Net Calls
+$19K
Net Calls Change
+$183K
Name Holding Trade Value Shares
Change
Change in
Stake
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$7.46M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$6.58M -$6.32M -353,492 -39%
BlackRock
3
BlackRock
New York
$4.96M -$111K -6,213 -1%
AG
4
Artal Group
Luxembourg
$4.17M +$894K +50,000 +17%
ABG
5
Ally Bridge Group
New York
$4M -$313K -17,500 -5%
FP
6
Flagship Pioneering
Massachusetts
$3.5M
OFM
7
Omega Fund Management
Massachusetts
$2.99M
Vanguard Group
8
Vanguard Group
Pennsylvania
$2.69M -$957K -53,484 -19%
SB
9
Samsara BioCapital
California
$2.26M -$518K -28,958 -13%
Adage Capital Partners
10
Adage Capital Partners
Massachusetts
$2.26M
State Street
11
State Street
Massachusetts
$1.36M -$17.2K -959 -0.8%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$1.17M +$57.3K +3,203 +3%
SCM
13
Sio Capital Management
New York
$1.07M +$3.99K +223 +0.2%
Renaissance Technologies
14
Renaissance Technologies
New York
$975K +$1.46M +81,896 New
CS
15
Candriam SCA
Luxembourg
$695K
Millennium Management
16
Millennium Management
New York
$609K +$750K +41,952 +455%
LCP
17
LGT Capital Partners
Switzerland
$595K
Northern Trust
18
Northern Trust
Illinois
$579K -$67.6K -3,780 -7%
GCP
19
GSA Capital Partners
United Kingdom
$443K +$233K +13,008 +54%
Los Angeles Capital Management
20
Los Angeles Capital Management
California
$297K -$14.7K -822 -3%
Federated Hermes
21
Federated Hermes
Pennsylvania
$286K +$135K +7,532 +46%
Dimensional Fund Advisors
22
Dimensional Fund Advisors
Texas
$263K -$168K -9,413 -30%
Goldman Sachs
23
Goldman Sachs
New York
$257K -$498K -27,829 -56%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$227K -$6.67K -373 -2%
Two Sigma Investments
25
Two Sigma Investments
New York
$222K +$246K +13,770 +283%

SYRS Hedge Fund Activity: Q1 2022 in Review

94 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q1 2022, worth a combined $53.1M — down 68% from $166M a quarter earlier.

Buyers outnumbered sellers: 15 funds opened new SYRS positions and 11 closed out — a net gain of 4 holders — while 26 added to existing stakes and 31 trimmed.

The largest buyer was Renaissance Technologies, opening a new position worth an estimated $1.46M. The largest seller was Fidelity Investments, cutting an estimated $6.32M.

  • 94 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q1 2022, up from 90 in Q4 2021.
  • Funds reported $53.1M of Syros Pharmaceuticals, Inc. Common Stock stock for Q1 2022, down 68% quarter-over-quarter.
  • 15 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q1 2022 and 11 closed out, a net change of +4 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q1 2022 was Renaissance Technologies, an estimated $1.46M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q1 2022 was Fidelity Investments, an estimated $6.32M sold.

Based on aggregated 13F filings for Q1 2022.