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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

58 hedge funds and large institutions have $147M invested in Syros Pharmaceuticals, Inc. Common Stock in 2023 Q4 according to their latest regulatory filings, with 16 funds opening new positions, 16 increasing their positions, 8 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

7,500% more call options, than puts

Call options by funds: $684K | Put options by funds: $9K

220% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 5

206% more capital invested

Capital invested by funds: $47.9M → $147M (+$98.9M)

100% more repeat investments, than reductions

Existing positions increased: 16 | Existing positions reduced: 8

21% more funds holding

Funds holding: 4858 (+10)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

Holders
58
Holders Change
+10
Holders Change %
+20.83%
% of All Funds
0.85%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
16
Increased
16
Reduced
8
Closed
5
Calls
$684K
Puts
$9K
Net Calls
+$675K
Net Calls Change
-$364K
Name Holding Trade Value Shares
Change
Change in
Stake
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$21.4M +$2.14M +625,114 +29%
AG
2
Artal Group
Luxembourg
$19.5M +$3.53M +1,029,269 +70%
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$16.1M +$4.62M +1,350,000 +187%
SB
4
Samsara BioCapital
California
$13.9M +$3.1M +904,977 +103%
APM
5
Avidity Partners Management
Texas
$13M +$316K +92,396 +6%
Point72 Asset Management
6
Point72 Asset Management
Connecticut
$11.5M +$5.04M +1,471,771 New
FP
7
Flagship Pioneering
Massachusetts
$10.1M +$1.03M +300,000 +30%
BOCH
8
Blue Owl Capital Holdings
New York
$8.46M +$5.11M +1,493,252 New
DTC
9
Deep Track Capital
Connecticut
$6.45M
Vanguard Group
10
Vanguard Group
Pennsylvania
$5.96M +$810K +236,620 +45%
OM
11
Opaleye Management
Massachusetts
$2.8M +$1.23M +359,370 New
OFM
12
Omega Fund Management
Massachusetts
$1.96M
BlackRock
13
BlackRock
New York
$1.92M +$4.11K +1,199 +0.5%
Goldman Sachs
14
Goldman Sachs
New York
$1.87M +$456K +133,149 +125%
DCM
15
DAFNA Capital Management
California
$1.67M -$175K -50,993 -19%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$1.26M +$81.2K +23,698 +17%
UOC
17
UBS O'Connor
Illinois
$1.01M +$445K +130,000 New
ECM
18
ExodusPoint Capital Management
New York
$806K -$15.8K -4,615 -4%
TCM
19
Tang Capital Management
California
$662K +$291K +85,031 New
EI
20
EAM Investors
California
$654K +$288K +84,002 New
LPL Financial
21
LPL Financial
California
$635K -$29.6K -8,650 -10%
DMKJ
22
David M. Knott Jr
$623K -$89.2K -26,048 -25%
Renaissance Technologies
23
Renaissance Technologies
New York
$457K +$32.2K +9,400 +19%
LCP
24
LGT Capital Partners
Switzerland
$428K
Two Sigma Investments
25
Two Sigma Investments
New York
$426K +$187K +54,654 New

SYRS Hedge Fund Activity: Q4 2023 in Review

58 of the 6,859 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q4 2023, worth a combined $147M — up 206% from $47.9M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new SYRS positions and 5 closed out — a net gain of 11 holders — while 16 added to existing stakes and 8 trimmed.

The largest buyer was Blue Owl Capital Holdings, opening a new position worth an estimated $5.11M. The largest seller was DAFNA Capital Management, cutting an estimated $175K.

  • 58 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q4 2023, up from 48 in Q3 2023.
  • Funds reported $147M of Syros Pharmaceuticals, Inc. Common Stock stock for Q4 2023, up 206% quarter-over-quarter.
  • 16 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q4 2023 and 5 closed out, a net change of +11 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q4 2023 was Blue Owl Capital Holdings, an estimated $5.11M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q4 2023 was DAFNA Capital Management, an estimated $175K sold.

Based on aggregated 13F filings for Q4 2023.