SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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101 hedge funds and large institutions have $590M invested in Syros Pharmaceuticals, Inc. Common Stock in 2020 Q4 according to their latest regulatory filings, with 25 funds opening new positions, 36 increasing their positions, 29 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
101
Holders Change
+8
Holders Change %
+8.6%
% of All Funds
1.79%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.07%
New
25
Increased
36
Reduced
29
Closed
16
Calls
$1.7M
Puts
$1.3M
Net Calls
+$400K
Net Calls Change
+$413K

Top Buyers

1
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$62.8M
2
O
OrbiMed
New York
+$17M
3
OFM
Omega Fund Management
Massachusetts
+$17M
4
EC
EcoR1 Capital
California
+$10.9M
5
AG
Artal Group
Luxembourg
+$3.09M

Top Sellers

1
AIM
ARK Investment Management
Florida
-$23.6M
2
State Street
State Street
Massachusetts
-$10.6M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$5.82M
4
SCM
Sio Capital Management
New York
-$1.47M
5
PCM
Portolan Capital Management
Massachusetts
-$748K
Name Holding Trade Value Shares
Change 		Shares
Change %
AIM
1
ARK Investment Management
Florida
$98.1M -$23.6M -217,119 -19%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$72.1M +$79.1K +729 +0.1%
BCLSI
3
Bain Capital Life Sciences Investors
Massachusetts
$62.8M +$62.8M +578,504 New
NAMA
4
Nikko Asset Management Americas
New York
$47.5M +$2.17M +19,964 +5%
Sumitomo Mitsui Trust Group
5
Sumitomo Mitsui Trust Group
Japan
$47.5M +$2.17M +19,964 +5%
BlackRock
6
BlackRock
New York
$36.1M +$170K +1,569 +0.5%
FP
7
Flagship Pioneering
Massachusetts
$31.9M – – –
ABG
8
Ally Bridge Group
New York
$28.7M +$28.7M +264,250 New
Vanguard Group
9
Vanguard Group
Pennsylvania
$22.2M +$122K +1,128 +0.6%
O
10
OrbiMed
New York
$17M +$17M +156,250 New
OFM
11
Omega Fund Management
Massachusetts
$17M +$17M +156,250 New
EC
12
EcoR1 Capital
California
$10.9M +$10.9M +100,000 New
AG
13
Artal Group
Luxembourg
$8.14M +$3.09M +28,450 +61%
JPMorgan Chase & Co
14
JPMorgan Chase & Co
New York
$7.98M +$34.1K +314 +0.4%
State Street
15
State Street
Massachusetts
$7.89M -$10.6M -97,254 -57%
BBA
16
Baker Bros. Advisors
New York
$7.49M – – –
Geode Capital Management
17
Geode Capital Management
Massachusetts
$6.4M +$102K +939 +2%
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$5.48M -$626K -5,772 -10%
Northern Trust
19
Northern Trust
Illinois
$4.9M -$109K -1,005 -2%
PCM
20
Portolan Capital Management
Massachusetts
$4.14M -$748K -6,894 -15%
Millennium Management
21
Millennium Management
New York
$4.13M +$2.49M +22,924 +152%
Charles Schwab
22
Charles Schwab
California
$2.64M -$1.74K -16 -0.1%
D.E. Shaw & Co
23
D.E. Shaw & Co
New York
$2.54M +$461K +4,251 +22%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$2.5M +$528K +4,870 +27%
RG
25
Redmile Group
California
$2.3M – – –
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