SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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70 hedge funds and large institutions have $291M invested in Syros Pharmaceuticals, Inc. Common Stock in 2019 Q4 according to their latest regulatory filings, with 17 funds opening new positions, 31 increasing their positions, 14 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
70
Holders Change
+8
Holders Change %
+12.9%
% of All Funds
1.38%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.06%
New
17
Increased
31
Reduced
14
Closed
9
Calls
$956K
Puts
–
Net Calls
+$956K
Net Calls Change
-$592K

Top Buyers

1
AIM
ARK Investment Management
Florida
+$8.59M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$3.63M
3
Millennium Management
Millennium Management
New York
+$3.5M
4
SCM
Sio Capital Management
New York
+$3.1M
5
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group
Japan
+$2.36M

Top Sellers

1
RG
Redmile Group
California
-$25.4M
2
6CM
683 Capital Management
New York
-$4.46M
3
AVM
Arch Venture Management
Illinois
-$3.74M
4
BBA
Baker Bros. Advisors
New York
-$1.97M
5
CS
Candriam SCA
Luxembourg
-$1.75M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$42.4M +$3.11K +45 +0%
AIM
2
ARK Investment Management
Florida
$35.1M +$8.59M +124,308 +32%
Sumitomo Mitsui Trust Group
3
Sumitomo Mitsui Trust Group
Japan
$34.4M +$2.36M +34,089 +7%
NAMA
4
Nikko Asset Management Americas
New York
$34.4M +$2.36M +34,089 +7%
AVM
5
Arch Venture Management
Illinois
$22.9M -$3.74M -54,123 -14%
FP
6
Flagship Pioneering
Massachusetts
$20.3M – – –
BlackRock
7
BlackRock
New York
$19.8M +$820K +11,865 +4%
Vanguard Group
8
Vanguard Group
Pennsylvania
$12.4M +$9.74K +141 +0.1%
SB
9
Samsara BioCapital
California
$11.3M – – –
DM
10
Deerfield Management
New York
$8.77M – – –
JPMorgan Chase & Co
11
JPMorgan Chase & Co
New York
$6.54M +$3.63M +52,550 +125%
BBA
12
Baker Bros. Advisors
New York
$4.77M -$1.97M -28,467 -29%
State Street
13
State Street
Massachusetts
$4.72M +$60.1K +870 +1%
Millennium Management
14
Millennium Management
New York
$3.63M +$3.5M +50,681 +2,699%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$3.47M +$186K +2,691 +6%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$3.29M +$167K +2,412 +5%
SCM
17
Sio Capital Management
New York
$3.1M +$3.1M +44,853 New
Northern Trust
18
Northern Trust
Illinois
$2.77M -$175K -2,535 -6%
PCM
19
Portolan Capital Management
Massachusetts
$2.26M +$2.26M +32,685 New
RG
20
Redmile Group
California
$1.47M -$25.4M -367,646 -95%
Charles Schwab
21
Charles Schwab
California
$1.42M +$43.3K +626 +3%
D.E. Shaw & Co
22
D.E. Shaw & Co
New York
$1.02M +$513K +7,414 +102%
Nuveen Asset Management
23
Nuveen Asset Management
Illinois
$972K +$228K +3,299 +31%
Renaissance Technologies
24
Renaissance Technologies
New York
$892K -$1.09M -15,751 -55%
Bank of New York Mellon
25
Bank of New York Mellon
New York
$770K -$761 -11 -0.1%
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