SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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62 hedge funds and large institutions have $446M invested in Syros Pharmaceuticals, Inc. Common Stock in 2019 Q3 according to their latest regulatory filings, with 5 funds opening new positions, 25 increasing their positions, 16 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
62
Holders Change
-6
Holders Change %
-8.82%
% of All Funds
1.36%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.07%
New
5
Increased
25
Reduced
16
Closed
11
Calls
$1.56M
Puts
$13K
Net Calls
+$1.55M
Net Calls Change
+$620K

Top Buyers

1
AVM
Arch Venture Management
Illinois
+$40M
2
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group
Japan
+$31.6M
3
NAMA
Nikko Asset Management Americas
New York
+$17.1M
4
RG
Redmile Group
California
+$2.79M
5
State Street
State Street
Massachusetts
+$1.15M

Top Sellers

1
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$2.94M
2
FP
Flagship Pioneering
Massachusetts
-$2.76M
3
EC
EcoR1 Capital
California
-$2.3M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$678K
5
Los Angeles Capital Management
Los Angeles Capital Management
California
-$374K
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$63.7M +$5.4K +52 +0%
NAMA
2
Nikko Asset Management Americas
New York
$48.1M +$17.1M +164,601 +55%
Sumitomo Mitsui Trust Group
3
Sumitomo Mitsui Trust Group
Japan
$48.1M +$31.6M +304,472 +192%
RG
4
Redmile Group
California
$40.4M +$2.79M +26,837 +7%
AVM
5
Arch Venture Management
Illinois
$40M +$40M +385,505 New
AIM
6
ARK Investment Management
Florida
$39.8M +$446K +4,297 +1%
FP
7
Flagship Pioneering
Massachusetts
$30.5M -$2.76M -26,595 -8%
BlackRock
8
BlackRock
New York
$28.5M +$805K +7,760 +3%
Vanguard Group
9
Vanguard Group
Pennsylvania
$18.6M +$318K +3,068 +2%
SB
10
Samsara BioCapital
California
$17M – – –
DM
11
Deerfield Management
New York
$13.2M – – –
BBA
12
Baker Bros. Advisors
New York
$10.1M – – –
State Street
13
State Street
Massachusetts
$7M +$1.15M +11,093 +20%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$4.93M – – –
Geode Capital Management
15
Geode Capital Management
Massachusetts
$4.69M +$57.2K +551 +1%
6CM
16
683 Capital Management
New York
$4.46M – – –
Northern Trust
17
Northern Trust
Illinois
$4.43M +$988K +9,520 +29%
JPMorgan Chase & Co
18
JPMorgan Chase & Co
New York
$4.37M +$132K +1,275 +3%
Renaissance Technologies
19
Renaissance Technologies
New York
$2.98M -$112K -1,080 -4%
Charles Schwab
20
Charles Schwab
California
$2.07M -$50.7K -488 -2%
CS
21
Candriam SCA
Luxembourg
$1.75M – – –
Bank of New York Mellon
22
Bank of New York Mellon
New York
$1.16M +$57.7K +556 +5%
Nuveen Asset Management
23
Nuveen Asset Management
Illinois
$1.12M -$45.2K -436 -4%
T. Rowe Price Associates
24
T. Rowe Price Associates
Maryland
$801K -$678K -6,527 -46%
Invesco
25
Invesco
Georgia
$801K +$801K +7,721 New
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