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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

62 hedge funds and large institutions have $446M invested in Syros Pharmaceuticals, Inc. Common Stock in 2019 Q3 according to their latest regulatory filings, with 5 funds opening new positions, 25 increasing their positions, 16 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

11,908% more call options, than puts

Call options by funds: $1.56M | Put options by funds: $13K

56% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 16

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

39% more capital invested

Capital invested by funds: $321M → $446M (+$125M)

9% less funds holding

Funds holding: 6862 (-6)

55% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 11

Holders
62
Holders Change
-6
Holders Change %
-8.82%
% of All Funds
1.36%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.07%
New
5
Increased
25
Reduced
16
Closed
11
Calls
$1.56M
Puts
$13K
Net Calls
+$1.55M
Net Calls Change
+$620K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$63.7M +$4.91K +52 +0%
NAMA
2
Nikko Asset Management Americas
New York
$48.1M +$15.5M +164,601 +55%
Sumitomo Mitsui Trust Group
3
Sumitomo Mitsui Trust Group
Japan
$48.1M +$28.8M +304,472 +192%
RG
4
Redmile Group
California
$40.4M +$2.53M +26,837 +7%
AVM
5
Arch Venture Management
Illinois
$40M +$36.4M +385,505 New
AIM
6
ARK Investment Management
Florida
$39.8M +$406K +4,297 +1%
FP
7
Flagship Pioneering
Massachusetts
$30.5M -$2.51M -26,595 -8%
BlackRock
8
BlackRock
New York
$28.5M +$733K +7,760 +3%
Vanguard Group
9
Vanguard Group
Pennsylvania
$18.6M +$290K +3,068 +2%
SB
10
Samsara BioCapital
California
$17M
DM
11
Deerfield Management
New York
$13.2M
BBA
12
Baker Bros. Advisors
New York
$10.1M
State Street
13
State Street
Massachusetts
$7M +$1.05M +11,093 +20%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$4.93M
Geode Capital Management
15
Geode Capital Management
Massachusetts
$4.68M +$52K +551 +1%
6CM
16
683 Capital Management
New York
$4.46M
Northern Trust
17
Northern Trust
Illinois
$4.43M +$899K +9,520 +29%
JP Morgan Chase
18
JP Morgan Chase
New York
$4.37M +$120K +1,275 +3%
Renaissance Technologies
19
Renaissance Technologies
New York
$2.98M -$102K -1,080 -4%
Charles Schwab
20
Charles Schwab
California
$2.07M -$46.1K -488 -2%
CS
21
Candriam SCA
Luxembourg
$1.75M
Bank of New York Mellon
22
Bank of New York Mellon
New York
$1.16M +$52.5K +556 +5%
N
23
Nuveen
North Carolina
$1.12M -$41.2K -436 -4%
T. Rowe Price Associates
24
T. Rowe Price Associates
Maryland
$801K -$616K -6,527 -46%
Invesco
25
Invesco
Georgia
$801K +$729K +7,721 New

SYRS Hedge Fund Activity: Q3 2019 in Review

62 of the 4,561 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q3 2019, worth a combined $446M — up 39% from $321M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of SYRS and 5 opened new positions — a net loss of 6 holders — while 16 trimmed existing stakes and 25 added.

The largest buyer was Arch Venture Management, opening a new position worth an estimated $36.4M. The largest seller was Alyeska Investment Group, exiting entirely with an estimated $3M sold.

  • 62 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q3 2019, down from 68 in Q2 2019.
  • Funds reported $446M of Syros Pharmaceuticals, Inc. Common Stock stock for Q3 2019, up 39% quarter-over-quarter.
  • 5 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q3 2019 and 11 closed out, a net change of -6 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q3 2019 was Arch Venture Management, an estimated $36.4M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q3 2019 was Alyeska Investment Group, an estimated $3M sold.

Based on aggregated 13F filings for Q3 2019.