SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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42 hedge funds and large institutions have $157M invested in Syros Pharmaceuticals, Inc. Common Stock in 2016 Q4 according to their latest regulatory filings, with 12 funds opening new positions, 12 increasing their positions, 7 reducing their positions, and 5 closing their positions.

Holders
42
Holders Change
+7
Holders Change %
+20%
% of All Funds
1.05%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
12
Increased
12
Reduced
7
Closed
5
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
CC
1
Casdin Capital
New York
$2.22M
2
RG
2
Redmile Group
California
$11.5M
3
Northern Trust
3
Northern Trust
Illinois
$329K
4
State Street
4
State Street
Massachusetts
$554K
5
Vanguard Group
5
Vanguard Group
Pennsylvania
$430K

Top Sellers

1
FCMI
1
Foresite Capital Management III
California
$0
2
COPPSERS
2
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$0
3
HLA
3
Hamilton Lane Advisors
Pennsylvania
$0
4
Goldman Sachs
4
Goldman Sachs
New York
$170K
5
SIM
5
Spark Investment Management
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
FP
1
Flagship Pioneering
Massachusetts
$58.4M 4,806,656 – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
$42.6M 3,507,070 +915 +0%
DM
3
Deerfield Management
New York
$22M 1,812,778 – –
RG
4
Redmile Group
California
$11.5M 948,440 +55,658 +6%
AC
5
Aisling Capital
New York
$6.18M 508,565 – –
BBA
6
Baker Bros. Advisors
New York
$2.49M 204,465 – –
CC
7
Casdin Capital
New York
$2.22M 182,141 +132,141 +264%
EAM
8
Eventide Asset Management
Massachusetts
$1.82M 150,000 – –
BFA
9
BlackRock Fund Advisors
California
$1.75M 144,045 +19,411 +16%
JPMorgan Chase & Co
10
JPMorgan Chase & Co
New York
$1.57M 129,118 -7,289 -5%
Alyeska Investment Group
11
Alyeska Investment Group
Illinois
$1.38M 113,543 +906 +0.8%
EC
12
EcoR1 Capital
California
$773K 63,596 – –
WMSA
13
Weiss Multi-Strategy Advisers
New York
$596K 49,000 – –
AIC
14
AWM Investment Company
New York
$578K 47,550 – –
State Street
15
State Street
Massachusetts
$554K 45,447 +20,468 +82%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$435K 35,836 +1,086 +3%
Vanguard Group
17
Vanguard Group
Pennsylvania
$430K 35,367 +19,940 +129%
Morgan Stanley
18
Morgan Stanley
New York
$377K 31,044 -2,770 -8%
Northern Trust
19
Northern Trust
Illinois
$329K 27,048 +27,048 New
BIT
20
BlackRock Institutional Trust
California
$198K 16,249 +9,792 +152%
Goldman Sachs
21
Goldman Sachs
New York
$170K 13,959 -15,498 -53%
California State Teachers Retirement System (CalSTRS)
22
California State Teachers Retirement System (CalSTRS)
California
$117K 9,600 -300 -3%
GT
23
Glenmede Trust
Pennsylvania
$113K 9,324 – –
New York State Common Retirement Fund
24
New York State Common Retirement Fund
New York
$61K 5,000 +5,000 New
TA
25
Teachers Advisors
New York
$60K 4,933 – –
1
2