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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

57 hedge funds and large institutions have $37.8M invested in Syros Pharmaceuticals, Inc. Common Stock in 2022 Q4 according to their latest regulatory filings, with 14 funds opening new positions, 12 increasing their positions, 14 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

4,795% more call options, than puts

Call options by funds: $1.08M | Put options by funds: $22K

56% more first-time investments, than exits

New positions opened: 14 | Existing positions closed: 9

8% more funds holding

Funds holding: 5357 (+4)

14% less repeat investments, than reductions

Existing positions increased: 12 | Existing positions reduced: 14

37% less capital invested

Capital invested by funds: $60.1M → $37.8M (-$22.3M)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
57
Holders Change
+4
Holders Change %
+7.55%
% of All Funds
0.92%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
14
Increased
12
Reduced
14
Closed
9
Calls
$1.08M
Puts
$22K
Net Calls
+$1.05M
Net Calls Change
-$829K
Name Holding Trade Value Shares
Change
Change in
Stake
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$7.63M +$4.52M +1,042,290 +96%
AG
2
Artal Group
Luxembourg
$5.25M
FP
3
Flagship Pioneering
Massachusetts
$3.57M
APM
4
Avidity Partners Management
Texas
$3.23M
SB
5
Samsara BioCapital
California
$3.16M
ABG
6
Ally Bridge Group
New York
$3.12M
Adage Capital Partners
7
Adage Capital Partners
Massachusetts
$2.59M
Vanguard Group
8
Vanguard Group
Pennsylvania
$1.7M -$64.2K -14,803 -3%
CH
9
CVI Holdings
Delaware
$1.53M
ACM
10
Altium Capital Management
New York
$1.13M +$1.37M +315,070 New
DCM
11
DAFNA Capital Management
California
$955K
OFM
12
Omega Fund Management
Massachusetts
$902K
BlackRock
13
BlackRock
New York
$746K -$163K -37,514 -15%
Millennium Management
14
Millennium Management
New York
$328K +$94.8K +21,839 +31%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$253K +$438 +101 +0.1%
LCP
16
LGT Capital Partners
Switzerland
$197K
Renaissance Technologies
17
Renaissance Technologies
New York
$170K +$15.2K +3,500 +8%
Susquehanna International Group
18
Susquehanna International Group
Pennsylvania
$155K +$143K +33,042 +324%
LPL Financial
19
LPL Financial
California
$147K +$126K +29,145 +246%
ECM
20
ExodusPoint Capital Management
New York
$123K +$148K +34,165 New
State Street
21
State Street
Massachusetts
$119K -$9 -2 -0%
1CM
22
1492 Capital Management
Wisconsin
$78.1K +$94.3K +21,744 New
CGL
23
Clarius Group LLC
Washington
$67K -$3.15K -727 -4%
E
24
Ergoteles
New York
$65.3K +$78.9K +18,181 New
Acadian Asset Management
25
Acadian Asset Management
Massachusetts
$62K -$29.6K -6,823 -28%

SYRS Hedge Fund Activity: Q4 2022 in Review

57 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q4 2022, worth a combined $37.8M — down 37% from $60.1M a quarter earlier.

Buyers outnumbered sellers: 14 funds opened new SYRS positions and 9 closed out — a net gain of 5 holders — while 12 added to existing stakes and 14 trimmed.

The largest buyer was Bain Capital Life Sciences Investors, adding an estimated $4.52M. The largest seller was Fidelity Investments, cutting an estimated $1.09M.

  • 57 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q4 2022, up from 53 in Q3 2022.
  • Funds reported $37.8M of Syros Pharmaceuticals, Inc. Common Stock stock for Q4 2022, down 37% quarter-over-quarter.
  • 14 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q4 2022 and 9 closed out, a net change of +5 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q4 2022 was Bain Capital Life Sciences Investors, an estimated $4.52M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q4 2022 was Fidelity Investments, an estimated $1.09M sold.

Based on aggregated 13F filings for Q4 2022.