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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

65 hedge funds and large institutions have $218M invested in Syros Pharmaceuticals, Inc. Common Stock in 2019 Q1 according to their latest regulatory filings, with 7 funds opening new positions, 24 increasing their positions, 23 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

76% more capital invested

Capital invested by funds: $124M → $218M (+$93.9M)

4% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 23

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

4% less funds holding

Funds holding: 6865 (-3)

30% less first-time investments, than exits

New positions opened: 7 | Existing positions closed: 10

Holders
65
Holders Change
-3
Holders Change %
-4.41%
% of All Funds
1.41%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
7
Increased
24
Reduced
23
Closed
10
Calls
$247K
Puts
Net Calls
+$247K
Net Calls Change
+$162K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$46.1M
FP
2
Flagship Pioneering
Massachusetts
$29.3M
AIM
3
ARK Investment Management
Florida
$27.4M +$3.71M +53,208 +22%
BlackRock
4
BlackRock
New York
$18.4M +$169K +2,429 +1%
RG
5
Redmile Group
California
$15M -$30.2K -434 -0.3%
DM
6
Deerfield Management
New York
$11.6M
SB
7
Samsara BioCapital
California
$9.69M
Vanguard Group
8
Vanguard Group
Pennsylvania
$8.24M +$1.54M +22,180 +33%
NAMA
9
Nikko Asset Management Americas
New York
$6.26M +$4.75M +68,246 +33,785%
Sumitomo Mitsui Trust Group
10
Sumitomo Mitsui Trust Group
Japan
$6.26M +$4.77M +68,448 New
BBA
11
Baker Bros. Advisors
New York
$5.25M
State Street
12
State Street
Massachusetts
$3.85M +$75K +1,077 +3%
JP Morgan Chase
13
JP Morgan Chase
New York
$3.67M -$4.81K -69 -0.2%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$3.32M +$831K +11,936 +49%
Northern Trust
15
Northern Trust
Illinois
$2.8M +$1.95K +28 +0.1%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$2.65M +$285K +4,086 +16%
Renaissance Technologies
17
Renaissance Technologies
New York
$2.02M +$667K +9,580 +77%
CS
18
Candriam SCA
Luxembourg
$1.86M
T. Rowe Price Associates
19
T. Rowe Price Associates
Maryland
$1.44M -$1.06M -15,263 -49%
Connor, Clark & Lunn Investment Management (CC&L)
20
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.09M -$25.8K -370 -3%
Charles Schwab
21
Charles Schwab
California
$1.03M -$98.5K -1,414 -11%
D.E. Shaw & Co
22
D.E. Shaw & Co
New York
$1.03M +$166K +2,381 +27%
WCM
23
Wedge Capital Management
North Carolina
$762K +$153K +2,194 +36%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$761K -$8.98K -129 -2%
AA
25
ALPS Advisors
Colorado
$743K +$24.5K +352 +5%

SYRS Hedge Fund Activity: Q1 2019 in Review

65 of the 4,621 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q1 2019, worth a combined $218M — up 76% from $124M a quarter earlier.

Sellers outnumbered buyers: 10 funds closed out of SYRS and 7 opened new positions — a net loss of 3 holders — while 23 trimmed existing stakes and 24 added.

The largest buyer was Sumitomo Mitsui Trust Group, opening a new position worth an estimated $4.77M. The largest seller was Point72 Asset Management, exiting entirely with an estimated $1.34M sold.

  • 65 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q1 2019, down from 68 in Q4 2018.
  • Funds reported $218M of Syros Pharmaceuticals, Inc. Common Stock stock for Q1 2019, up 76% quarter-over-quarter.
  • 7 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q1 2019 and 10 closed out, a net change of -3 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q1 2019 was Sumitomo Mitsui Trust Group, an estimated $4.77M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q1 2019 was Point72 Asset Management, an estimated $1.34M sold.

Based on aggregated 13F filings for Q1 2019.