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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

75 hedge funds and large institutions have $112M invested in Syros Pharmaceuticals, Inc. Common Stock in 2024 Q1 according to their latest regulatory filings, with 22 funds opening new positions, 21 increasing their positions, 7 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

5,300% more call options, than puts

Call options by funds: $162K | Put options by funds: $3K

340% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 5

200% more repeat investments, than reductions

Existing positions increased: 21 | Existing positions reduced: 7

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

29% more funds holding

Funds holding: 5875 (+17)

24% less capital invested

Capital invested by funds: $147M → $112M (-$34.9M)

Holders
75
Holders Change
+17
Holders Change %
+29.31%
% of All Funds
1.08%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
22
Increased
21
Reduced
7
Closed
5
Calls
$162K
Puts
$3K
Net Calls
+$159K
Net Calls Change
-$516K
Name Holding Trade Value Shares
Change
Change in
Stake
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$14.7M
AG
2
Artal Group
Luxembourg
$13.4M
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$11.1M
SB
4
Samsara BioCapital
California
$9.56M
APM
5
Avidity Partners Management
Texas
$8.95M
Point72 Asset Management
6
Point72 Asset Management
Connecticut
$7.87M
FP
7
Flagship Pioneering
Massachusetts
$6.92M +$7 +1 +0%
Vanguard Group
8
Vanguard Group
Pennsylvania
$4.97M +$1.13M +163,234 +21%
DTC
9
Deep Track Capital
Connecticut
$4.43M
OM
10
Opaleye Management
Massachusetts
$4.21M +$2.96M +428,175 +119%
Goldman Sachs
11
Goldman Sachs
New York
$2.39M +$1.43M +206,910 +86%
KCM
12
Kennedy Capital Management
Missouri
$2.17M +$2.8M +404,914 New
BOCH
13
Blue Owl Capital Holdings
New York
$1.82M -$7.97M -1,152,397 -77%
Walleye Capital
14
Walleye Capital
New York
$1.52M +$1.97M +284,936 New
Millennium Management
15
Millennium Management
New York
$1.4M +$1.81M +261,083 New
BlackRock
16
BlackRock
New York
$1.38M +$69.8K +10,097 +4%
OFM
17
Omega Fund Management
Massachusetts
$1.34M
DMKJ
18
David M. Knott Jr
$1.25M +$1.06M +153,073 +192%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$1.18M +$406K +58,682 +36%
UOC
20
UBS O'Connor
Illinois
$936K +$311K +45,000 +35%
Jane Street
21
Jane Street
New York
$923K +$1.05M +151,382 +716%
Assenagon Asset Management
22
Assenagon Asset Management
Luxembourg
$909K +$1M +144,869 +576%
Marshall Wace
23
Marshall Wace
United Kingdom
$854K +$932K +134,766 +543%
ECM
24
ExodusPoint Capital Management
New York
$829K +$356K +51,467 +50%
Qube Research & Technologies (QRT)
25
Qube Research & Technologies (QRT)
United Kingdom
$738K +$953K +137,881 New

SYRS Hedge Fund Activity: Q1 2024 in Review

75 of the 6,942 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q1 2024, worth a combined $112M — down 24% from $147M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new SYRS positions and 5 closed out — a net gain of 17 holders — while 21 added to existing stakes and 7 trimmed.

The largest buyer was Opaleye Management, adding an estimated $2.96M. The largest seller was Blue Owl Capital Holdings, cutting an estimated $7.97M.

  • 75 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q1 2024, up from 58 in Q4 2023.
  • Funds reported $112M of Syros Pharmaceuticals, Inc. Common Stock stock for Q1 2024, down 24% quarter-over-quarter.
  • 22 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q1 2024 and 5 closed out, a net change of +17 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q1 2024 was Opaleye Management, an estimated $2.96M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q1 2024 was Blue Owl Capital Holdings, an estimated $7.97M sold.

Based on aggregated 13F filings for Q1 2024.