SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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68 hedge funds and large institutions have $124M invested in Syros Pharmaceuticals, Inc. Common Stock in 2018 Q4 according to their latest regulatory filings, with 8 funds opening new positions, 25 increasing their positions, 22 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
68
Holders Change
-8
Holders Change %
-10.53%
% of All Funds
1.52%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.04%
New
8
Increased
25
Reduced
22
Closed
16
Calls
$85K
Puts
–
Net Calls
+$85K
Net Calls Change
-$100K

Top Buyers

1
BlackRock
BlackRock
New York
+$2.07M
2
AIM
ARK Investment Management
Florida
+$1.33M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$881K
4
Renaissance Technologies
Renaissance Technologies
New York
+$537K
5
Dimensional Fund Advisors
Dimensional Fund Advisors
Texas
+$522K

Top Sellers

1
Vanguard Group
Vanguard Group
Pennsylvania
-$2.03M
2
EAM
Eventide Asset Management
Massachusetts
-$1.79M
3
PP
PDT Partners
New York
-$618K
4
Millennium Management
Millennium Management
New York
-$427K
5
VEA
Virtus ETF Advisers
New York
-$424K
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$28.1M – – –
FP
2
Flagship Pioneering
Massachusetts
$17.8M – – –
AIM
3
ARK Investment Management
Florida
$13.7M +$1.33M +23,875 +11%
BlackRock
4
BlackRock
New York
$11.1M +$2.07M +37,246 +23%
RG
5
Redmile Group
California
$9.19M -$36.8K -660 -0.4%
DM
6
Deerfield Management
New York
$7.07M – – –
SB
7
Samsara BioCapital
California
$5.9M +$5.9M +105,994 New
Vanguard Group
8
Vanguard Group
Pennsylvania
$3.79M -$2.03M -36,480 -35%
BBA
9
Baker Bros. Advisors
New York
$3.2M – – –
State Street
10
State Street
Massachusetts
$2.28M +$157K +2,824 +7%
JPMorgan Chase & Co
11
JPMorgan Chase & Co
New York
$2.24M +$177K +3,180 +9%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$1.73M -$96.4K -1,730 -5%
Northern Trust
13
Northern Trust
Illinois
$1.71M +$12.1K +218 +0.7%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$1.39M +$129K +2,324 +10%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$1.36M +$522K +9,373 +62%
Point72 Asset Management
16
Point72 Asset Management
Connecticut
$1.34M +$881K +15,816 +193%
CS
17
Candriam SCA
Luxembourg
$1.14M – – –
Charles Schwab
18
Charles Schwab
California
$708K -$11.3K -203 -2%
Renaissance Technologies
19
Renaissance Technologies
New York
$695K +$537K +9,640 +341%
Connor, Clark & Lunn Investment Management (CC&L)
20
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$683K +$21.7K +390 +3%
Jacobs Levy Equity Management
21
Jacobs Levy Equity Management
New Jersey
$571K +$132K +2,360 +30%
Millennium Management
22
Millennium Management
New York
$536K -$427K -7,666 -44%
PAM
23
Panagora Asset Management
Massachusetts
$525K – – –
Assenagon Asset Management
24
Assenagon Asset Management
Luxembourg
$502K +$502K +9,020 New
D.E. Shaw & Co
25
D.E. Shaw & Co
New York
$496K +$439K +7,859 +764%
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