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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

68 hedge funds and large institutions have $124M invested in Syros Pharmaceuticals, Inc. Common Stock in 2018 Q4 according to their latest regulatory filings, with 8 funds opening new positions, 25 increasing their positions, 22 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

14% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 22

11% less funds holding

Funds holding: 7668 (-8)

50% less capital invested

Capital invested by funds: $246M → $124M (-$122M)

50% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 16

Holders
68
Holders Change
-8
Holders Change %
-10.53%
% of All Funds
1.51%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.04%
New
8
Increased
25
Reduced
22
Closed
16
Calls
$85K
Puts
Net Calls
+$85K
Net Calls Change
-$100K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$28.1M
FP
2
Flagship Pioneering
Massachusetts
$17.8M
AIM
3
ARK Investment Management
Florida
$13.7M +$1.81M +23,875 +11%
BlackRock
4
BlackRock
New York
$11.1M +$2.83M +37,246 +23%
RG
5
Redmile Group
California
$9.19M -$50.1K -660 -0.4%
DM
6
Deerfield Management
New York
$7.07M
SB
7
Samsara BioCapital
California
$5.9M +$8.05M +105,994 New
Vanguard Group
8
Vanguard Group
Pennsylvania
$3.79M -$2.77M -36,480 -35%
BBA
9
Baker Bros. Advisors
New York
$3.2M
State Street
10
State Street
Massachusetts
$2.28M +$215K +2,824 +7%
JP Morgan Chase
11
JP Morgan Chase
New York
$2.24M +$242K +3,180 +9%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$1.73M -$131K -1,730 -5%
Northern Trust
13
Northern Trust
Illinois
$1.71M +$16.6K +218 +0.7%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$1.39M +$177K +2,324 +10%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$1.36M +$712K +9,373 +62%
Point72 Asset Management
16
Point72 Asset Management
Connecticut
$1.34M +$1.2M +15,816 +193%
CS
17
Candriam SCA
Luxembourg
$1.14M
Charles Schwab
18
Charles Schwab
California
$708K -$15.4K -203 -2%
Renaissance Technologies
19
Renaissance Technologies
New York
$695K +$732K +9,640 +341%
Connor, Clark & Lunn Investment Management (CC&L)
20
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$683K +$29.6K +390 +3%
Jacobs Levy Equity Management
21
Jacobs Levy Equity Management
New Jersey
$571K +$179K +2,360 +30%
Millennium Management
22
Millennium Management
New York
$536K -$582K -7,666 -44%
PAM
23
Panagora Asset Management
Massachusetts
$525K
Assenagon Asset Management
24
Assenagon Asset Management
Luxembourg
$502K +$685K +9,020 New
D.E. Shaw & Co
25
D.E. Shaw & Co
New York
$496K +$597K +7,859 +764%

SYRS Hedge Fund Activity: Q4 2018 in Review

68 of the 4,489 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q4 2018, worth a combined $124M — down 50% from $246M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of SYRS and 8 opened new positions — a net loss of 8 holders — while 22 trimmed existing stakes and 25 added.

The largest buyer was BlackRock, adding an estimated $2.83M. The largest seller was Vanguard Group, cutting an estimated $2.77M.

  • 68 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q4 2018, down from 76 in Q3 2018.
  • Funds reported $124M of Syros Pharmaceuticals, Inc. Common Stock stock for Q4 2018, down 50% quarter-over-quarter.
  • 8 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q4 2018 and 16 closed out, a net change of -8 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q4 2018 was BlackRock, an estimated $2.83M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q4 2018 was Vanguard Group, an estimated $2.77M sold.

Based on aggregated 13F filings for Q4 2018.