SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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79 hedge funds and large institutions have $464M invested in Syros Pharmaceuticals, Inc. Common Stock in 2020 Q2 according to their latest regulatory filings, with 20 funds opening new positions, 36 increasing their positions, 16 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
79
Holders Change
+15
Holders Change %
+23.44%
% of All Funds
1.62%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.06%
New
20
Increased
36
Reduced
16
Closed
5
Calls
$941K
Puts
–
Net Calls
+$941K
Net Calls Change
+$330K

Top Buyers

1
AIM
ARK Investment Management
Florida
+$27.9M
2
BlackRock
BlackRock
New York
+$5.4M
3
Fidelity Investments
Fidelity Investments
Massachusetts
+$3.67M
4
Two Sigma Investments
Two Sigma Investments
New York
+$2.63M
5
State Street
State Street
Massachusetts
+$2.05M

Top Sellers

1
AVM
Arch Venture Management
Illinois
-$28.4M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
-$7.9M
3
DM
Deerfield Management
New York
-$7.53M
4
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group
Japan
-$2.14M
5
SCM
Sio Capital Management
New York
-$2.09M
Name Holding Trade Value Shares
Change 		Shares
Change %
AIM
1
ARK Investment Management
Florida
$90.8M +$27.9M +261,373 +44%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$70.6M +$3.67M +34,422 +5%
Sumitomo Mitsui Trust Group
3
Sumitomo Mitsui Trust Group
Japan
$50.4M -$2.14M -20,044 -4%
NAMA
4
Nikko Asset Management Americas
New York
$38.9M -$1.75M -21,162 -4%
BlackRock
5
BlackRock
New York
$35.4M +$5.4M +50,695 +18%
FP
6
Flagship Pioneering
Massachusetts
$31.3M – – –
Vanguard Group
7
Vanguard Group
Pennsylvania
$20.3M +$1.1M +10,300 +6%
Point72 Asset Management
8
Point72 Asset Management
Connecticut
$16.4M -$7.9M -74,108 -33%
SB
9
Samsara BioCapital
California
$15.9M -$1.56M -15,470 -9%
State Street
10
State Street
Massachusetts
$9.01M +$2.05M +19,202 +29%
JPMorgan Chase & Co
11
JPMorgan Chase & Co
New York
$8.46M -$941K -8,829 -10%
BBA
12
Baker Bros. Advisors
New York
$7.36M – – –
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$6.01M – – –
Geode Capital Management
14
Geode Capital Management
Massachusetts
$6.01M +$699K +6,561 +13%
PCM
15
Portolan Capital Management
Massachusetts
$5.32M -$148K -1,390 -3%
Northern Trust
16
Northern Trust
Illinois
$5.25M +$902K +8,464 +21%
AG
17
Artal Group
Luxembourg
$5.22M -$172K -1,614 -3%
AVM
18
Arch Venture Management
Illinois
$4.26M -$28.4M -266,382 -87%
SCM
19
Sio Capital Management
New York
$2.91M -$2.09M -19,563 -42%
Charles Schwab
20
Charles Schwab
California
$2.68M +$487K +4,572 +22%
Two Sigma Investments
21
Two Sigma Investments
New York
$2.63M +$2.63M +24,700 New
D.E. Shaw & Co
22
D.E. Shaw & Co
New York
$2.48M +$1.57M +14,761 +174%
RG
23
Redmile Group
California
$2.26M – – –
Nuveen Asset Management
24
Nuveen Asset Management
Illinois
$2.17M +$689K +6,466 +47%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$1.94M +$1.09M +10,190 +127%
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