SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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57 hedge funds and large institutions have $240M invested in Syros Pharmaceuticals, Inc. Common Stock in 2018 Q1 according to their latest regulatory filings, with 7 funds opening new positions, 27 increasing their positions, 10 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
57
Holders Change
-12
Holders Change %
-17.39%
% of All Funds
1.31%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
7
Increased
27
Reduced
10
Closed
19
Calls
$332K
Puts
$111K
Net Calls
+$221K
Net Calls Change
+$460K

Top Buyers

1
RG
Redmile Group
California
+$13.2M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$11.5M
3
AIM
ARK Investment Management
Florida
+$8.7M
4
BlackRock
BlackRock
New York
+$4.6M
5
Vanguard Group
Vanguard Group
Pennsylvania
+$4.37M

Top Sellers

1
AC
Aisling Capital
New York
-$4.95M
2
CAM
Cormorant Asset Management
Massachusetts
-$2.88M
3
CC
Casdin Capital
New York
-$2.67M
4
AIC
AWM Investment Company
New York
-$632K
5
Russell Investments Group
Russell Investments Group
United Kingdom
-$330K
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$62.7M +$11.5M +88,462 +22%
FP
2
Flagship Pioneering
Massachusetts
$41.6M – – –
RG
3
Redmile Group
California
$21.4M +$13.2M +101,501 +159%
AIM
4
ARK Investment Management
Florida
$19.5M +$8.7M +67,013 +80%
DM
5
Deerfield Management
New York
$16.5M – – –
Wellington Management Group
6
Wellington Management Group
Massachusetts
$13.4M +$442K +3,408 +3%
BlackRock
7
BlackRock
New York
$12.1M +$4.6M +35,459 +62%
Vanguard Group
8
Vanguard Group
Pennsylvania
$11.9M +$4.37M +33,676 +58%
BBA
9
Baker Bros. Advisors
New York
$7.46M – – –
JPMorgan Chase & Co
10
JPMorgan Chase & Co
New York
$4.86M +$593K +4,571 +14%
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$4.25M +$225K +1,732 +6%
CS
12
Candriam SCA
Luxembourg
$2.65M -$77.9K -600 -3%
State Street
13
State Street
Massachusetts
$2.62M +$144K +1,110 +6%
Northern Trust
14
Northern Trust
Illinois
$2.35M +$609K +4,693 +35%
Millennium Management
15
Millennium Management
New York
$2.13M +$2.13M +16,377 New
Geode Capital Management
16
Geode Capital Management
Massachusetts
$2.12M +$880K +6,781 +71%
EAM
17
Eventide Asset Management
Massachusetts
$1.95M – – –
GCP
18
GSA Capital Partners
United Kingdom
$1.41M +$1.41M +10,890 New
BCM
19
Bridgeway Capital Management
Texas
$1.29M +$1.29M +9,970 New
Charles Schwab
20
Charles Schwab
California
$997K +$433K +3,331 +77%
OM
21
Opaleye Management
Massachusetts
$961K – – –
PP
22
PDT Partners
New York
$849K +$46.6K +359 +6%
Connor, Clark & Lunn Investment Management (CC&L)
23
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$744K +$554K +4,270 +292%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$670K +$213K +1,637 +46%
TCIM
25
TIAA CREF Investment Management
New York
$508K +$113K +869 +29%
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