We are live on ! Find out more
SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

57 hedge funds and large institutions have $240M invested in Syros Pharmaceuticals, Inc. Common Stock in 2018 Q1 according to their latest regulatory filings, with 7 funds opening new positions, 27 increasing their positions, 10 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

199% more call options, than puts

Call options by funds: $332K | Put options by funds: $111K

170% more repeat investments, than reductions

Existing positions increased: 27 | Existing positions reduced: 10

55% more capital invested

Capital invested by funds: $154M → $240M (+$85.7M)

17% less funds holding

Funds holding: 6957 (-12)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

63% less first-time investments, than exits

New positions opened: 7 | Existing positions closed: 19

Holders
57
Holders Change
-12
Holders Change %
-17.39%
% of All Funds
1.31%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
7
Increased
27
Reduced
10
Closed
19
Calls
$332K
Puts
$111K
Net Calls
+$221K
Net Calls Change
+$460K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$62.7M +$9.67M +88,462 +22%
FP
2
Flagship Pioneering
Massachusetts
$41.6M
RG
3
Redmile Group
California
$21.4M +$11.1M +101,501 +159%
AIM
4
ARK Investment Management
Florida
$19.5M +$7.33M +67,013 +80%
DM
5
Deerfield Management
New York
$16.5M
Wellington Management Group
6
Wellington Management Group
Massachusetts
$13.4M +$373K +3,408 +3%
BlackRock
7
BlackRock
New York
$12.1M +$3.88M +35,459 +62%
Vanguard Group
8
Vanguard Group
Pennsylvania
$11.9M +$3.68M +33,676 +58%
BBA
9
Baker Bros. Advisors
New York
$7.46M
JP Morgan Chase
10
JP Morgan Chase
New York
$4.86M +$500K +4,571 +14%
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$4.25M +$189K +1,732 +6%
CS
12
Candriam SCA
Luxembourg
$2.65M -$65.6K -600 -3%
State Street
13
State Street
Massachusetts
$2.62M +$121K +1,110 +6%
Northern Trust
14
Northern Trust
Illinois
$2.35M +$513K +4,693 +35%
Millennium Management
15
Millennium Management
New York
$2.13M +$1.79M +16,377 New
Geode Capital Management
16
Geode Capital Management
Massachusetts
$2.12M +$741K +6,781 +71%
EAM
17
Eventide Asset Management
Massachusetts
$1.95M
GCP
18
GSA Capital Partners
United Kingdom
$1.41M +$1.19M +10,890 New
BCM
19
Bridgeway Capital Management
Texas
$1.29M +$1.09M +9,970 New
Charles Schwab
20
Charles Schwab
California
$997K +$364K +3,331 +77%
OM
21
Opaleye Management
Massachusetts
$961K
PP
22
PDT Partners
New York
$849K +$39.3K +359 +6%
Connor, Clark & Lunn Investment Management (CC&L)
23
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$744K +$467K +4,270 +292%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$670K +$179K +1,637 +46%
TCIM
25
TIAA CREF Investment Management
New York
$508K +$95K +869 +29%

SYRS Hedge Fund Activity: Q1 2018 in Review

57 of the 4,364 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q1 2018, worth a combined $240M — up 55% from $154M a quarter earlier.

Sellers outnumbered buyers: 19 funds closed out of SYRS and 7 opened new positions — a net loss of 12 holders — while 10 trimmed existing stakes and 27 added.

The largest buyer was Redmile Group, adding an estimated $11.1M. The largest seller was Aisling Capital, exiting entirely with an estimated $4.95M sold.

  • 57 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q1 2018, down from 69 in Q4 2017.
  • Funds reported $240M of Syros Pharmaceuticals, Inc. Common Stock stock for Q1 2018, up 55% quarter-over-quarter.
  • 7 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q1 2018 and 19 closed out, a net change of -12 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q1 2018 was Redmile Group, an estimated $11.1M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q1 2018 was Aisling Capital, an estimated $4.95M sold.

Based on aggregated 13F filings for Q1 2018.