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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

100 hedge funds and large institutions have $223M invested in Syros Pharmaceuticals, Inc. Common Stock in 2021 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 29 increasing their positions, 34 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

7% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 15

0% more funds holding

Funds holding: 100100 (0)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

15% less repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 34

19% less capital invested

Capital invested by funds: $276M → $223M (-$52.9M)

86% less call options, than puts

Call options by funds: $224K | Put options by funds: $1.55M

Holders
100
Holders Change
Holders Change %
0%
% of All Funds
1.75%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
16
Increased
29
Reduced
34
Closed
15
Calls
$224K
Puts
$1.55M
Net Calls
-$1.32M
Net Calls Change
+$446K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$40.5M +$53.1K +1,088 +0.1%
BCLSI
2
Bain Capital Life Sciences Investors
Massachusetts
$25.9M
BlackRock
3
BlackRock
New York
$19.5M -$535K -10,969 -2%
ABG
4
Ally Bridge Group
New York
$15.4M
Vanguard Group
5
Vanguard Group
Pennsylvania
$13.3M +$1.03M +21,040 +8%
FP
6
Flagship Pioneering
Massachusetts
$13.1M
OFM
7
Omega Fund Management
Massachusetts
$11.2M +$1.16M +23,788 +10%
AG
8
Artal Group
Luxembourg
$8.94M +$1.46M +30,000 +18%
SB
9
Samsara BioCapital
California
$8.62M
O
10
OrbiMed
New York
$8.21M
Adage Capital Partners
11
Adage Capital Partners
Massachusetts
$8.05M +$4.63M +94,770 +111%
ACM
12
Altium Capital Management
New York
$5.69M +$954K +19,547 +18%
State Street
13
State Street
Massachusetts
$4.99M +$568K +11,632 +12%
SCM
14
Sio Capital Management
New York
$4.03M +$492K +10,068 +13%
RCM
15
RA Capital Management
Massachusetts
$4.02M
Geode Capital Management
16
Geode Capital Management
Massachusetts
$3.83M -$531K -10,880 -11%
CS
17
Candriam SCA
Luxembourg
$2.61M
Northern Trust
18
Northern Trust
Illinois
$2.35M -$145K -2,974 -5%
Goldman Sachs
19
Goldman Sachs
New York
$2.19M -$52.3K -1,072 -2%
Millennium Management
20
Millennium Management
New York
$1.41M -$1.18M -24,133 -43%
Los Angeles Capital Management
21
Los Angeles Capital Management
California
$1.16M -$61.4K -1,257 -5%
Morgan Stanley
22
Morgan Stanley
New York
$1.02M -$849K -17,391 -43%
N
23
Nuveen
North Carolina
$1.01M +$88.2K +1,807 +10%
Susquehanna International Group
24
Susquehanna International Group
Pennsylvania
$953K +$326K +6,674 +46%
Dimensional Fund Advisors
25
Dimensional Fund Advisors
Texas
$918K -$505K -10,335 -33%

SYRS Hedge Fund Activity: Q3 2021 in Review

100 of the 5,712 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q3 2021, worth a combined $223M — down 19% from $276M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new SYRS positions and 15 closed out — a net gain of 1 holder — while 29 added to existing stakes and 34 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $4.63M. The largest seller was EcoR1 Capital, exiting entirely with an estimated $5.45M sold.

  • 100 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q3 2021, unchanged from Q2 2021.
  • Funds reported $223M of Syros Pharmaceuticals, Inc. Common Stock stock for Q3 2021, down 19% quarter-over-quarter.
  • 16 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q3 2021 and 15 closed out, a net change of +1 holder.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q3 2021 was Adage Capital Partners, an estimated $4.63M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q3 2021 was EcoR1 Capital, an estimated $5.45M sold.

Based on aggregated 13F filings for Q3 2021.